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PLK1 phosphorylates PAX3-FOXO1, the inhibition of which triggers regression of alveolar Rhabdomyosarcoma.
Thalhammer, Verena; Lopez-Garcia, Laura A; Herrero-Martin, David; Hecker, Regina; Laubscher, Dominik; Gierisch, Maria E; Wachtel, Marco; Bode, Peter; Nanni, Paolo; Blank, Bernd; Koscielniak, Ewa; Schäfer, Beat W.
Afiliação
  • Thalhammer V; Department of Oncology and Children's Research Center, University Children's Hospital Zurich, Zurich, Switzerland.
  • Lopez-Garcia LA; Department of Oncology and Children's Research Center, University Children's Hospital Zurich, Zurich, Switzerland.
  • Herrero-Martin D; Department of Oncology and Children's Research Center, University Children's Hospital Zurich, Zurich, Switzerland.
  • Hecker R; Department of Oncology and Children's Research Center, University Children's Hospital Zurich, Zurich, Switzerland.
  • Laubscher D; Department of Oncology and Children's Research Center, University Children's Hospital Zurich, Zurich, Switzerland.
  • Gierisch ME; Department of Oncology and Children's Research Center, University Children's Hospital Zurich, Zurich, Switzerland.
  • Wachtel M; Department of Oncology and Children's Research Center, University Children's Hospital Zurich, Zurich, Switzerland.
  • Bode P; Department of Surgical Pathology, University Hospital Zurich, Zurich, Switzerland.
  • Nanni P; Functional Genomics Center Zurich, University of Zurich, Zurich, Switzerland.
  • Blank B; Department of Oncology/Hematology/Immunology, Olgahospital, Klinikum Stuttgart, Stuttgart, Germany.
  • Koscielniak E; Department of Oncology/Hematology/Immunology, Olgahospital, Klinikum Stuttgart, Stuttgart, Germany.
  • Schäfer BW; Department of Oncology and Children's Research Center, University Children's Hospital Zurich, Zurich, Switzerland. Beat.Schaefer@kispi.uzh.ch.
Cancer Res ; 75(1): 98-110, 2015 Jan 01.
Article em En | MEDLINE | ID: mdl-25398439
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Fusão Oncogênica / Proteínas Proto-Oncogênicas / Proteínas Serina-Treonina Quinases / Rabdomiossarcoma Alveolar / Proteínas de Ciclo Celular / Fatores de Transcrição Box Pareados Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Fusão Oncogênica / Proteínas Proto-Oncogênicas / Proteínas Serina-Treonina Quinases / Rabdomiossarcoma Alveolar / Proteínas de Ciclo Celular / Fatores de Transcrição Box Pareados Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2015 Tipo de documento: Article