Fractal globules: a new approach to artificial molecular machines.
Biophys J
; 107(10): 2361-8, 2014 Nov 18.
Article
em En
| MEDLINE
| ID: mdl-25418305
ABSTRACT
The over-damped relaxation of elastic networks constructed by contact maps of hierarchically folded fractal (crumpled) polymer globules was investigated in detail. It was found that the relaxation dynamics of an anisotropic fractal globule is very similar to the behavior of biological molecular machines like motor proteins. When it is perturbed, the system quickly relaxes to a low-dimensional manifold, M, with a large basin of attraction and then slowly approaches equilibrium, not escaping M. Taking these properties into account, it is suggested that fractal globules, even those made by synthetic polymers, are artificial molecular machines that can transform perturbations into directed quasimechanical motion along a defined path.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Polímeros
/
Fractais
/
Biomimética
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article