[New Developments in CKD-MBD. Bone quality and fracture in patients with chronic kidney disease].
Clin Calcium
; 24(12): 1809-14, 2014 Dec.
Article
em Ja
| MEDLINE
| ID: mdl-25423926
ABSTRACT
Chronic kidney disease (CKD) patients have an extremely increased risk of fragility fractures, but the underling pathophysiological mechanisms remain obscure. Recently, the progresses of analysis technology have revealed the changes of bone quality in CKD condition. In particular, we can observe the characteristic changes of bone microarchitecture and bone chemical compositions in both human bone biopsy samples and experimental animal bones. Here, I will provide a short review on these bone quality factors and discuss on the relationship between bone quality and fracture in CKD patients.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Doenças Ósseas Metabólicas
/
Densidade Óssea
/
Insuficiência Renal Crônica
/
Fraturas Ósseas
Tipo de estudo:
Etiology_studies
Limite:
Animals
/
Humans
Idioma:
Ja
Ano de publicação:
2014
Tipo de documento:
Article