Human metapneumovirus pneumonia in patients with hematological malignancies.
J Clin Virol
; 61(4): 593-6, 2014 Dec.
Article
em En
| MEDLINE
| ID: mdl-25440914
ABSTRACT
BACKGROUND:
Human metapneumovirus (HMPV) has recently emerged as a cause of respiratory infections in hematological patients. Clinical data are lacking to guide the management of HMPV pneumonias.OBJECTIVES:
To characterize the clinical and radiographic presentation and outcome of HMPV pneumonias diagnosed in hematological patients. STUDYDESIGN:
We screened the patients with a positive HMPV respiratory test in two French teaching hospitals between 2007 and 2011. Among them, the medical charts from the hematological patients who presented with HMPV pneumonia were reviewed.RESULTS:
Among the 54 patients with several underlying hematological conditions who were positive for HMPV, we found 13 cases of HMPV pneumonias. HMPV could be the cause of pneumonia as a single pathogen without associated upper respiratory infection. Centrilobular nodules were constant on lung computed tomography scans. No patients died despite the absence of administration of antiviral treatments.CONCLUSIONS:
Our data provide further insights in the diagnosis and management of HMPV pneumonias in this setting.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Pneumonia Viral
/
Infecções por Paramyxoviridae
/
Neoplasias Hematológicas
/
Metapneumovirus
Tipo de estudo:
Diagnostic_studies
Limite:
Adolescent
/
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
País/Região como assunto:
Europa
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article