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Benefits of an intraoral stent in decreasing the irradiation dose to oral healthy tissue: dosimetric and clinical features.
Verrone, Juliana Rocha; Alves, Fabio Abreu; Prado, José Divaldo; Marcicano, Alessandra das Dores; de Assis Pellizzon, Antonio Cassio; Damascena, Aline Santos; Jaguar, Graziella Chagas.
Afiliação
  • Verrone JR; Stomatology Department, A.C. Camargo Cancer Center, São Paulo, São Paulo, Brazil.
  • Alves FA; Stomatology Department, A.C. Camargo Cancer Center, São Paulo, São Paulo, Brazil.
  • Prado JD; Stomatology Department, A.C. Camargo Cancer Center, São Paulo, São Paulo, Brazil.
  • Marcicano Ad; Radiotherapy Department, A.C. Camargo Cancer Center, São Paulo, São Paulo, Brazil.
  • de Assis Pellizzon AC; Radiotherapy Department, A.C. Camargo Cancer Center, São Paulo, São Paulo, Brazil.
  • Damascena AS; Statistics Department, A.C. Camargo Cancer Center, São Paulo, São Paulo, Brazil.
  • Jaguar GC; Stomatology Department, A.C. Camargo Cancer Center, São Paulo, São Paulo, Brazil. Electronic address: valoiscruz@bol.com.br.
Article em En | MEDLINE | ID: mdl-25442494
ABSTRACT

OBJECTIVE:

To determine whether an intraoral stent may decrease radiation dose to health tissues during intensity-modulated radiotherapy (IMRT) and to evaluate the effect on mucositis. STUDY

DESIGN:

A total of 33 patients with tongue or floor of the mouth cancer were retrospectively evaluated and divided into 2 groups group 1 (with stent, n = 19) and group 2 (without stent, n = 14). Data were collected on dosimetric and mucositis outcomes.

RESULTS:

The mean dose to the maxilla was significantly lower in group 1 (20.9 Gy) than in group 2 (35.8 Gy) (P = .05). The mean dose to the ipsilateral parotid was 35.0 Gy in group 1 vs 41.8 Gy in group 2 (P = .05). No difference was seen in the severity of mucositis between groups (P = .82). However, grade III mucositis was present in group 1 at 4 weeks after IMRT, 1 week after its occurrence in group 2.

CONCLUSIONS:

A stent was effective in decreasing doses to healthy structures and delaying the emergence of mucositis.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Lesões por Radiação / Proteção Radiológica / Neoplasias Bucais / Stents / Mucosite / Radioterapia de Intensidade Modulada Tipo de estudo: Observational_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2014 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Lesões por Radiação / Proteção Radiológica / Neoplasias Bucais / Stents / Mucosite / Radioterapia de Intensidade Modulada Tipo de estudo: Observational_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2014 Tipo de documento: Article