[Chronic maternal diseases and pregnancy losses. French guidelines]. / Pathologies maternelles chroniques et pertes de grossesse. Recommandations françaises.
J Gynecol Obstet Biol Reprod (Paris)
; 43(10): 865-82, 2014 Dec.
Article
em Fr
| MEDLINE
| ID: mdl-25447366
ABSTRACT
AIM:
To review the available data on maternal chronic diseases and pregnancy losses. MATERIAL ANDMETHODS:
We searched PubMed and the Cochrane library with pregnancy loss, stillbirth, intrauterine fetal demise, intrauterine fetal death, miscarriage and each maternal diseases of this paper.RESULTS:
Antiphospholipid antibodies (anticardiolipin, anti-beta-2-glycoprotein, lupus anticoagulant) should be measured in case of miscarriage after 10WG confirmed by ultrasound (grade B) and an antiphospholipid syndrome should be treated by a combination of aspirin and low-molecular-weight heparin during a subsequent pregnancy (grade A). We do not recommend testing for genetic thrombophilia in case of first trimester miscarriage (grade B) or stillbirth (grade C). Glycemic control should be a goal before pregnancy for women with pregestational diabetes to limit the risks of pregnancy loss (grade A) with a goal of prepregnancy HbA1c<7%. Overt and subclinical hypothyroidisms should be treated by L-thyroxin during pregnancy to reduce the risks of pregnancy loss (grade A). Women who are positive for TPOAb should have TSH concentrations follow-up during pregnancy and subsequently treated by L-thyroxin if they develop subclinical hypothyroidism (grade B).CONCLUSIONS:
Prepregnancy management of most chronic maternal diseases, ideally through prepregnancy multidisciplinary counseling, reduces the risks of pregnancy loss.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Complicações na Gravidez
/
Aborto Espontâneo
/
Doença Crônica
/
Guias de Prática Clínica como Assunto
/
Morte Fetal
Tipo de estudo:
Guideline
Limite:
Female
/
Humans
/
Pregnancy
País/Região como assunto:
Europa
Idioma:
Fr
Ano de publicação:
2014
Tipo de documento:
Article