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Identification of the remains of King Richard III.
King, Turi E; Fortes, Gloria Gonzalez; Balaresque, Patricia; Thomas, Mark G; Balding, David; Maisano Delser, Pierpaolo; Neumann, Rita; Parson, Walther; Knapp, Michael; Walsh, Susan; Tonasso, Laure; Holt, John; Kayser, Manfred; Appleby, Jo; Forster, Peter; Ekserdjian, David; Hofreiter, Michael; Schürer, Kevin.
Afiliação
  • King TE; 1] Department of Genetics, University of Leicester, Leicester LE1 7RH, UK [2] School of Archaeology and Ancient History, University of Leicester, Leicester LE1 7RH, UK.
  • Fortes GG; 1] Department of Biology, University of York, York YO10 5DD, UK [2] Institute of Biochemistry and Biology, Universität Potsdam, Karl-Liebknechtstr. 24-25, 14476 Potsdam, Germany.
  • Balaresque P; UMR5288-CNRS/Université Paul Sabatier-Toulouse 3 Laboratoire Anthropologie Moléculaire et Imagerie de Synthèse Faculté de Médecine Purpam 37, allées Jules Guesde, 31073 Toulouse, France.
  • Thomas MG; Research Department of Genetics, Evolution and Environment, University College London, London WC1E 6BT, UK.
  • Balding D; Research Department of Genetics, Evolution and Environment, University College London, London WC1E 6BT, UK.
  • Maisano Delser P; Department of Genetics, University of Leicester, Leicester LE1 7RH, UK.
  • Neumann R; Department of Genetics, University of Leicester, Leicester LE1 7RH, UK.
  • Parson W; 1] Institute of Legal Medicine, Innsbruck Medical University, Muellerstraße 44, A-6020 Innsbruck, Austria [2] Pennsylvania State University, Eberly College of Science, Thomas Bldg, #517, University Park, Pennsylvania 16802, USA.
  • Knapp M; School of Biological Sciences, Bangor University, Bangor LL57 2UW, UK.
  • Walsh S; 1] Molecular Anthropology Laboratory, Department of Anthropology, Yale University, Yale, New Haven, Connecticut 06511, USA [2] Department of Forensic Molecular Biology, Erasmus MC University Medical Centre Rotterdam, 3000 CA Rotterdam, The Netherlands.
  • Tonasso L; UMR5288-CNRS/Université Paul Sabatier-Toulouse 3 Laboratoire Anthropologie Moléculaire et Imagerie de Synthèse Faculté de Médecine Purpam 37, allées Jules Guesde, 31073 Toulouse, France.
  • Holt J; Space Research Centre, University of Leicester, Leicester LE1 7RH, UK.
  • Kayser M; Department of Forensic Molecular Biology, Erasmus MC University Medical Centre Rotterdam, 3000 CA Rotterdam, The Netherlands.
  • Appleby J; School of Archaeology and Ancient History, University of Leicester, Leicester LE1 7RH, UK.
  • Forster P; 1] McDonald Institute for Archaeological Research, University of Cambridge, Cambridge CB2 3ER, UK [2] Murray Edwards College, University of Cambridge, Cambridge CB3 0DF, UK.
  • Ekserdjian D; Department of the History of Art and Film, University of Leicester, Leicester LE1 7RH, UK.
  • Hofreiter M; 1] Department of Biology, University of York, York YO10 5DD, UK [2] Institute of Biochemistry and Biology, Universität Potsdam, Karl-Liebknechtstr. 24-25, 14476 Potsdam, Germany.
  • Schürer K; Centre for English Local History, University of Leicester, Leicester LE1 7RH, UK.
Nat Commun ; 5: 5631, 2014 Dec 02.
Article em En | MEDLINE | ID: mdl-25463651
ABSTRACT
In 2012, a skeleton was excavated at the presumed site of the Grey Friars friary in Leicester, the last-known resting place of King Richard III. Archaeological, osteological and radiocarbon dating data were consistent with these being his remains. Here we report DNA analyses of both the skeletal remains and living relatives of Richard III. We find a perfect mitochondrial DNA match between the sequence obtained from the remains and one living relative, and a single-base substitution when compared with a second relative. Y-chromosome haplotypes from male-line relatives and the remains do not match, which could be attributed to a false-paternity event occurring in any of the intervening generations. DNA-predicted hair and eye colour are consistent with Richard's appearance in an early portrait. We calculate likelihood ratios for the non-genetic and genetic data separately, and combined, and conclude that the evidence for the remains being those of Richard III is overwhelming.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: DNA Mitocondrial / Impressões Digitais de DNA / Cromossomos Humanos Y / Genética Forense Tipo de estudo: Diagnostic_studies Limite: Humans / Male Idioma: En Ano de publicação: 2014 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: DNA Mitocondrial / Impressões Digitais de DNA / Cromossomos Humanos Y / Genética Forense Tipo de estudo: Diagnostic_studies Limite: Humans / Male Idioma: En Ano de publicação: 2014 Tipo de documento: Article