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A naturally occurring single amino acid replacement in multiple gene regulator of group A Streptococcus significantly increases virulence.
Sanson, Misu; O'Neill, Brian E; Kachroo, Priyanka; Anderson, Jeff R; Flores, Anthony R; Valson, Chandni; Cantu, Concepcion C; Makthal, Nishanth; Karmonik, Christof; Fittipaldi, Nahuel; Kumaraswami, Muthiah; Musser, James M; Olsen, Randall J.
Afiliação
  • Sanson M; Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Center for Molecular and Translational Human Infectious Diseases Research, Houston, Texas; School of Biotechnology, School of Medicine and Health Sciences, Tecnológico de Monterrey, Monterrey, Mexico.
  • O'Neill BE; Department of Translational Imaging, MRI Core, Houston Methodist Research Institute, Houston, Texas.
  • Kachroo P; Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Center for Molecular and Translational Human Infectious Diseases Research, Houston, Texas.
  • Anderson JR; Department of Translational Imaging, MRI Core, Houston Methodist Research Institute, Houston, Texas.
  • Flores AR; Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Center for Molecular and Translational Human Infectious Diseases Research, Houston, Texas; Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Houston, Texas.
  • Valson C; Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Center for Molecular and Translational Human Infectious Diseases Research, Houston, Texas.
  • Cantu CC; Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Center for Molecular and Translational Human Infectious Diseases Research, Houston, Texas.
  • Makthal N; Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Center for Molecular and Translational Human Infectious Diseases Research, Houston, Texas.
  • Karmonik C; Department of Translational Imaging, MRI Core, Houston Methodist Research Institute, Houston, Texas.
  • Fittipaldi N; Department of Laboratory Medicine and Pathobiology, Public Health Ontario, University of Toronto, Toronto, Ontario, Canada.
  • Kumaraswami M; Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Center for Molecular and Translational Human Infectious Diseases Research, Houston, Texas.
  • Musser JM; Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Center for Molecular and Translational Human Infectious Diseases Research, Houston, Texas.
  • Olsen RJ; Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Center for Molecular and Translational Human Infectious Diseases Research, Houston, Texas. Electronic address: rjolsen@houstonmethodist.org.
Am J Pathol ; 185(2): 462-71, 2015 Feb.
Article em En | MEDLINE | ID: mdl-25476528
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecções Estreptocócicas / Streptococcus pyogenes / Proteínas de Bactérias / Mutação de Sentido Incorreto / Polimorfismo de Nucleotídeo Único / Artropatias Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecções Estreptocócicas / Streptococcus pyogenes / Proteínas de Bactérias / Mutação de Sentido Incorreto / Polimorfismo de Nucleotídeo Único / Artropatias Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article