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Epigenetic dysregulation of hairy and enhancer of split 4 (HES4) is associated with striatal degeneration in postmortem Huntington brains.
Bai, Guang; Cheung, Iris; Shulha, Hennady P; Coelho, Joana E; Li, Ping; Dong, Xianjun; Jakovcevski, Mira; Wang, Yumei; Grigorenko, Anastasia; Jiang, Yan; Hoss, Andrew; Patel, Krupal; Zheng, Ming; Rogaev, Evgeny; Myers, Richard H; Weng, Zhiping; Akbarian, Schahram; Chen, Jiang-Fan.
Afiliação
  • Bai G; Department of Neural and Pain Sciences, University of Maryland Dental School, Baltimore, MD 21201, USA.
  • Cheung I; Brudnick Neuropsychiatric Research Institute.
  • Shulha HP; Program in Bioinformatics and Integrative Biology, Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01604, USA.
  • Coelho JE; Department of Neurology, Boston University School of Medicine, 715 Albany Street, Boston, MA 02118, USA.
  • Li P; Department of Neurology, Boston University School of Medicine, 715 Albany Street, Boston, MA 02118, USA.
  • Dong X; Program in Bioinformatics and Integrative Biology, Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01604, USA.
  • Jakovcevski M; Brudnick Neuropsychiatric Research Institute.
  • Wang Y; Department of Neurology, Boston University School of Medicine, 715 Albany Street, Boston, MA 02118, USA.
  • Grigorenko A; Brudnick Neuropsychiatric Research Institute.
  • Jiang Y; Friedman Brain Institute, Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA.
  • Hoss A; Department of Neurology, Boston University School of Medicine, 715 Albany Street, Boston, MA 02118, USA.
  • Patel K; Department of Neural and Pain Sciences, University of Maryland Dental School, Baltimore, MD 21201, USA.
  • Zheng M; Department of Neural and Pain Sciences, University of Maryland Dental School, Baltimore, MD 21201, USA.
  • Rogaev E; Brudnick Neuropsychiatric Research Institute.
  • Myers RH; Department of Neurology, Boston University School of Medicine, 715 Albany Street, Boston, MA 02118, USA, Genome Science Institute, Boston University School of Medicine, 72 East Concord Street, Boston, MA 02118, USA.
  • Weng Z; Program in Bioinformatics and Integrative Biology, Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01604, USA.
  • Akbarian S; Brudnick Neuropsychiatric Research Institute, Friedman Brain Institute, Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA.
  • Chen JF; Department of Neurology, Boston University School of Medicine, 715 Albany Street, Boston, MA 02118, USA, chenjf@bu.edu.
Hum Mol Genet ; 24(5): 1441-56, 2015 Mar 01.
Article em En | MEDLINE | ID: mdl-25480889

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neostriado / Doença de Huntington / Proteínas de Homeodomínio / Epigênese Genética / Fatores de Transcrição Hélice-Alça-Hélice Básicos Tipo de estudo: Observational_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male Idioma: En Ano de publicação: 2015 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neostriado / Doença de Huntington / Proteínas de Homeodomínio / Epigênese Genética / Fatores de Transcrição Hélice-Alça-Hélice Básicos Tipo de estudo: Observational_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male Idioma: En Ano de publicação: 2015 Tipo de documento: Article