Quantitative dual-energy CT for phantomless evaluation of cancellous bone mineral density of the vertebral pedicle: correlation with pedicle screw pull-out strength.
Eur Radiol
; 25(6): 1714-20, 2015 Jun.
Article
em En
| MEDLINE
| ID: mdl-25481639
ABSTRACT
OBJECTIVES:
To evaluate quantitative dual-energy computed tomography (DECT) for phantomless analysis of cancellous bone mineral density (BMD) of vertebral pedicles and to assess the correlation with pedicle screw pull-out strength.METHODS:
Twenty-nine thoracic and lumbar vertebrae from cadaver specimens were examined with DECT. Using dedicated post-processing software, a pedicle screw vector was mapped (R1, intrapedicular segment of the pedicle vector; R2, intermediate segment; R3, intracorporal segment; global, all segments) and BMD was calculated. To invasively evaluate pedicle stability, pedicle screws were drilled through both pedicles and left pedicle screw pull-out strength was measured. Resulting values were correlated using the paired t test and Pearson's linear correlation.RESULTS:
Average pedicle screw vector BMD (R1, 0.232 g/cm(3); R2, 0.166 g/cm(3); R3, 0.173 g/cm(3); global, 0.236 g/cm(3)) showed significant differences between R1-R2 (P < 0.002) and R1-R3 (P < 0.034) segments while comparison of R2-R3 did not reach significance (P > 0.668). Average screw pull-out strength (639.2 N) showed a far stronger correlation with R1 (r = 0.80; P < 0.0001) than global BMD (r = 0.42; P = 0.025), R2 (r = 0.37; P = 0.048) and R3 (r = -0.33; P = 0.078) segments.CONCLUSIONS:
Quantitative DECT allows for phantomless BMD assessment of the vertebral pedicle. BMD of the intrapedicular segment shows a significantly stronger correlation with pedicle screw pull-out strength than other segments. KEY POINTS ⢠Quantitative dual-energy CT enables evaluation of pedicle bone mineral density. ⢠Intrapedicular segments show significant differences regarding bone mineral density. ⢠Pedicle screw pull-out strength correlated strongest with R1 values. ⢠Dual-energy CT may improve preoperative assessment before transpedicular screw fixation.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Vértebras Torácicas
/
Densidade Óssea
/
Parafusos Pediculares
/
Vértebras Lombares
Tipo de estudo:
Observational_studies
Limite:
Aged
/
Female
/
Humans
/
Male
Idioma:
En
Ano de publicação:
2015
Tipo de documento:
Article