Your browser doesn't support javascript.
loading
Three-Dimensional Flexible Electronics Enabled by Shape Memory Polymer Substrates for Responsive Neural Interfaces.
Ware, Taylor; Simon, Dustin; Hearon, Keith; Liu, Clive; Shah, Sagar; Reeder, Jonathan; Khodaparast, Navid; Kilgard, Michael P; Maitland, Duncan J; Rennaker, Robert L; Voit, Walter E.
Afiliação
  • Ware T; Assistant Professor, Department of Materials Science and Engineering, The University of Texas at Dallas, Mailstop RL10, 800 West Campbell Rd., Richardson, TX 75080, USA.
  • Simon D; Assistant Professor, Department of Materials Science and Engineering, The University of Texas at Dallas, Mailstop RL10, 800 West Campbell Rd., Richardson, TX 75080, USA.
  • Hearon K; Department of Biomedical Engineering, Texas A&M University, College Station, TX 77843, USA.
  • Liu C; Department of Mechanical Engineering, The University of Texas at Dallas, Mailstop RL10, 800 West Campbell Rd., Richardson, TX 75080, USA.
  • Shah S; Department of Molecular and Cell Biology, The University of Texas at Dallas, Mailstop RL10, 800 West Campbell Rd., Richardson, TX 75080, USA.
  • Reeder J; Department of Mechanical Engineering, The University of Texas at Dallas, Mailstop RL10, 800 West Campbell Rd., Richardson, TX 75080, USA.
  • Khodaparast N; Department of Behavioral and Brain Sciences, The University of Texas at Dallas, Mailstop RL10, 800 West Campbell Rd., Richardson, TX 75080, USA.
  • Kilgard MP; Department of Behavioral and Brain Sciences, The University of Texas at Dallas, Mailstop RL10, 800 West Campbell Rd., Richardson, TX 75080, USA.
  • Maitland DJ; Department of Biomedical Engineering, Texas A&M University, College Station, TX 77843, USA.
  • Rennaker RL; School of Behavioral and Brain Sciences, Erik Jonsson School of Engineering, The University of Texas at Dallas, Mailstop RL10, 800 West Campbell Rd., Richardson, TX 75080, USA.
  • Voit WE; Assistant Professor, Department of Materials Science and Engineering, The University of Texas at Dallas, Mailstop RL10, 800 West Campbell Rd., Richardson, TX 75080, USA.
Macromol Mater Eng ; 297(12): 1193-1202, 2012 Dec 01.
Article em En | MEDLINE | ID: mdl-25530708
ABSTRACT
Planar electronics processing methods have enabled neural interfaces to become more precise and deliver more information. However, this processing paradigm is inherently 2D and rigid. The resulting mechanical and geometrical mismatch at the biotic-abiotic interface can elicit an immune response that prevents effective stimulation. In this work, a thiol-ene/acrylate shape memory polymer is utilized to create 3D softening substrates for stimulation electrodes. This substrate system is shown to soften in vivo from more than 600 to 6 MPa. A nerve cuff electrode that coils around the vagus nerve in a rat and that drives neural activity is demonstrated.
Palavras-chave
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2012 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2012 Tipo de documento: Article