Your browser doesn't support javascript.
loading
Optimization and evaluation of reconstruction-based compensation methods and reconstruction parameters for Tc-99m MIBI parathyroid SPECT.
Ekjeen, Tawatchai; Tocharoenchai, Chiraporn; Pusuwan, Pawana; Fung, George S K; Ghaly, Michael; Du, Yong; Frey, Eric C.
Afiliação
  • Ekjeen T; Department of Radiological Technology, Faculty of Medical Technology, Mahidol University, Bangkok, Thailand. Electronic address: tawatchai.ekj@mahidol.ac.th.
  • Tocharoenchai C; Department of Radiological Technology, Faculty of Medical Technology, Mahidol University, Bangkok, Thailand.
  • Pusuwan P; Department of Radiology, Siriraj Hospital, Bangkok, Thailand.
  • Fung GS; The Russell H Morgan Department of Radiology and Radiological Science, Johns Hopkins University, Baltimore, MD, USA.
  • Ghaly M; The Russell H Morgan Department of Radiology and Radiological Science, Johns Hopkins University, Baltimore, MD, USA.
  • Du Y; The Russell H Morgan Department of Radiology and Radiological Science, Johns Hopkins University, Baltimore, MD, USA.
  • Frey EC; The Russell H Morgan Department of Radiology and Radiological Science, Johns Hopkins University, Baltimore, MD, USA.
Phys Med ; 31(2): 159-66, 2015 Mar.
Article em En | MEDLINE | ID: mdl-25555904
ABSTRACT
The value of Tc-99m MIBI parathyroid SPECT for localizing parathyroid hyperplasia in chronic renal failure patients remains inconclusive due to limited image quality. Advanced reconstruction methods to improve image quality have been developed but require optimization and evaluation. The goal of this study was to optimize and evaluate compensation methods and reconstruction parameters for Tc-99m MIBI parathyroid SPECT. A phantom population and projection data that modelled clinically realistic variations found in patients were simulated. The 3D OS-EM reconstruction with compensation for attenuation, detector response and scatter in various combinations were studied. For each compensation, the number of updates for OS-EM and the cutoff frequency of a 3D Butterworth filter were optimized and evaluated using anthropomorphic model observer. With optimal parameters, the method with compensation for attenuation and detector response, with or without the addition of scatter compensation, provided the highest lesion detectability for Tc-99m MIBI parathyroid SPECT.
Assuntos
Palavras-chave
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Glândulas Paratireoides / Processamento de Imagem Assistida por Computador / Tomografia Computadorizada de Emissão de Fóton Único / Tecnécio Tc 99m Sestamibi Tipo de estudo: Evaluation_studies / Prognostic_studies Limite: Female / Humans / Male Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Glândulas Paratireoides / Processamento de Imagem Assistida por Computador / Tomografia Computadorizada de Emissão de Fóton Único / Tecnécio Tc 99m Sestamibi Tipo de estudo: Evaluation_studies / Prognostic_studies Limite: Female / Humans / Male Idioma: En Ano de publicação: 2015 Tipo de documento: Article