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Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutations.
Deng, Kai; Pertea, Mihaela; Rongvaux, Anthony; Wang, Leyao; Durand, Christine M; Ghiaur, Gabriel; Lai, Jun; McHugh, Holly L; Hao, Haiping; Zhang, Hao; Margolick, Joseph B; Gurer, Cagan; Murphy, Andrew J; Valenzuela, David M; Yancopoulos, George D; Deeks, Steven G; Strowig, Till; Kumar, Priti; Siliciano, Janet D; Salzberg, Steven L; Flavell, Richard A; Shan, Liang; Siliciano, Robert F.
Afiliação
  • Deng K; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.
  • Pertea M; 1] Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA [2] Center for Computational Biology, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.
  • Rongvaux A; Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06510, USA.
  • Wang L; Department of Chronic Disease Epidemiology, Yale School of Public Health, New Haven, Connecticut 06510, USA.
  • Durand CM; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.
  • Ghiaur G; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.
  • Lai J; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.
  • McHugh HL; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.
  • Hao H; Deep Sequencing and Microarray Core, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.
  • Zhang H; Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA.
  • Margolick JB; Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA.
  • Gurer C; Regeneron Pharmaceuticals Inc., Tarrytown, New York 10591, USA.
  • Murphy AJ; Regeneron Pharmaceuticals Inc., Tarrytown, New York 10591, USA.
  • Valenzuela DM; Regeneron Pharmaceuticals Inc., Tarrytown, New York 10591, USA.
  • Yancopoulos GD; Regeneron Pharmaceuticals Inc., Tarrytown, New York 10591, USA.
  • Deeks SG; Department of Medicine, University of California, San Francisco, San Francisco, California 94110, USA.
  • Strowig T; Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06510, USA.
  • Kumar P; Department of Medicine, Yale University School of Medicine, New Haven, Connecticut 06510, USA.
  • Siliciano JD; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.
  • Salzberg SL; 1] Center for Computational Biology, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA [2] Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.
  • Flavell RA; 1] Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06510, USA [2] Howard Hughes Medical Institute, New Haven, Connecticut 06510, USA.
  • Shan L; Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06510, USA.
  • Siliciano RF; 1] Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA [2] Howard Hughes Medical Institute, Baltimore, Maryland 21205, USA.
Nature ; 517(7534): 381-5, 2015 Jan 15.
Article em En | MEDLINE | ID: mdl-25561180

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Linfócitos T Citotóxicos / HIV-1 / Latência Viral / Genes Dominantes / Genes Virais / Mutação Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2015 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Linfócitos T Citotóxicos / HIV-1 / Latência Viral / Genes Dominantes / Genes Virais / Mutação Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2015 Tipo de documento: Article