[Studies regarding the fixing of the zinc from ADH through some azopyrazolone]. / Cercetari privind modul de fixare a zincului din ADH prin intermediul unor azopirazolone.

ABSTRACT

The mechanism of reaction-between the zinc atom of alcohol dehydrogenase and 6 pyrazolone and azopyrazolone compounds, type 1-(4'-carboxyphenyl)-3-methyl-4(1"azo-4"-ethoxy-phenyl)-5-pyrazolone, synthetized by the authors, is studied. For elucidating the "in vivo" phenomenon, the complexes of these compounds were synthetized with zinc atoms, the IR specters and quantitative chemical analyses being followed. Based on these, the possibilities of complexing the zinc from the ADH molecule by these compounds are discussed.