Loss of periostin/OSF-2 in ErbB2/Neu-driven tumors results in androgen receptor-positive molecular apocrine-like tumors with reduced Notch1 activity.

Sriram, Roshan; Lo, Vivian; Pryce, Benjamin; Antonova, Lilia; Mears, Alan J; Daneshmand, Manijeh; McKay, Bruce; Conway, Simon J; Muller, William J; Sabourin, Luc A

Sriram, Roshan; Lo, Vivian; Pryce, Benjamin; Antonova, Lilia; Mears, Alan J; Daneshmand, Manijeh; McKay, Bruce; Conway, Simon J; Muller, William J; Sabourin, Luc A.

Afiliação

Sriram R; Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, 451 Smyth Road, Ottawa, ON, K1H 8M5, Canada. roshankumar2733@yahoo.com.
Lo V; Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, 451 Smyth Road, Ottawa, ON, K1H 8M5, Canada. vlo101@uottawa.ca.
Pryce B; Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, 451 Smyth Road, Ottawa, ON, K1H 8M5, Canada. bpryce89@gmail.com.
Antonova L; Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, 451 Smyth Road, Ottawa, ON, K1H 8M5, Canada. l_antonova@hotmail.com.
Mears AJ; Children's Hospital of Eastern Ontario, Research Institute, 501 Smyth Road, Ottawa, ON, K1H8L6, Canada. amears@cheo.on.ca.
Daneshmand M; Ottawa Hospital Research Institute, Cancer Therapeutics, 501 Smyth Road, Ottawa, ON, K1H 8L6, Canada. mdaneshmand@ohri.ca.
McKay B; Department of Biology and Institute of Biochemistry, Carleton University, 1125 Colonel By Drive, Ottawa, ON, K1S 5B6, Canada. Bruce_McKay@carleton.ca.
Conway SJ; Developmental Biology and Neonatal Medicine Program, HB Wells Center for Pediatric Research, Indiana University School of Medicine, 705 Riley Hospital Drive, Indianapolis, IN, 46202, USA. siconway@iu.edu.
Muller WJ; Department of Biochemistry and Goodman Cancer Research Center, McGill University, 1200 Pine Avenue West, Montreal, QC, H3G 1A1, Canada. william.muller@mcgill.ca.
Sabourin LA; Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, 451 Smyth Road, Ottawa, ON, K1H 8M5, Canada. lsabourin@ohri.ca.

Breast Cancer Res ; 17: 7, 2015 Jan 16.

Article em En | MEDLINE | ID: mdl-25592291

Assuntos

Moléculas de Adesão Celular/deficiência; Receptor ErbB-2/genética; Receptor ErbB-2/metabolismo; Receptor Notch1/metabolismo; Receptores Androgênicos/metabolismo; Neoplasias das Glândulas Sudoríparas/genética; Neoplasias das Glândulas Sudoríparas/metabolismo; Animais; Glândulas Apócrinas/metabolismo; Glândulas Apócrinas/patologia; Neoplasias da Mama/genética; Neoplasias da Mama/metabolismo; Neoplasias da Mama/patologia; Moléculas de Adesão Celular/genética; Moléculas de Adesão Celular/metabolismo; Transformação Celular Neoplásica/genética; Transformação Celular Neoplásica/metabolismo; Modelos Animais de Doenças; Feminino; Expressão Gênica; Genótipo; Humanos; Imuno-Histoquímica; Glândulas Mamárias Animais/metabolismo; Camundongos; Camundongos Knockout; Camundongos Transgênicos; Fenótipo; Neoplasias das Glândulas Sudoríparas/mortalidade; Neoplasias das Glândulas Sudoríparas/patologia; Carga Tumoral

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias das Glândulas Sudoríparas / Receptores Androgênicos / Moléculas de Adesão Celular / Receptor ErbB-2 / Receptor Notch1 Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google