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Smad7 regulates compensatory hepatocyte proliferation in damaged mouse liver and positively relates to better clinical outcome in human hepatocellular carcinoma.
Feng, Teng; Dzieran, Johanna; Gu, Xing; Marhenke, Silke; Vogel, Arndt; Machida, Keigo; Weiss, Thomas S; Ruemmele, Petra; Kollmar, Otto; Hoffmann, Patrick; Grässer, Friedrich; Allgayer, Heike; Fabian, Jasmin; Weng, Hong Lei; Teufel, Andreas; Maass, Thorsten; Meyer, Christoph; Lehmann, Ulrich; Zhu, Cheng; Mertens, Peter R; Gao, Chun Fang; Dooley, Steven; Meindl-Beinker, Nadja M.
Afiliação
  • Feng T; *Molecular Hepatology Alcohol Associated Diseases, Dept. of Medicine II, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
  • Dzieran J; *Molecular Hepatology Alcohol Associated Diseases, Dept. of Medicine II, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
  • Gu X; †Department of Laboratory Medicine, Eastern Hepatobiliary Hospital, Second Military Medical University, Shanghai, China.
  • Marhenke S; ‡Department of Gastroenterology, Hepatology and Endocrinology, Medical School Hannover, Hannover, Germany.
  • Vogel A; ‡Department of Gastroenterology, Hepatology and Endocrinology, Medical School Hannover, Hannover, Germany.
  • Machida K; §Department of Molecular Microbiology and Immunology and Southern California Research Center for ALPD and Cirrhosis, Los Angeles, CA, U.S.A.
  • Weiss TS; ║Department of Pediatrics and Juvenile Medicine, Center for Liver Cell Research, University of Regensburg Hospital, Regensburg, Germany.
  • Ruemmele P; ¶Institute of Pathology, University of Regensburg, Regensburg, Germany.
  • Kollmar O; **Department of General, Visceral, Vascular and Pediatric Surgery, University of Saarland, Homburg/Saar, Germany.
  • Hoffmann P; ††Saarland University Medical School, Institute of Virology, Homburg/Saar, Germany.
  • Grässer F; ††Saarland University Medical School, Institute of Virology, Homburg/Saar, Germany.
  • Allgayer H; ‡‡Department of Experimental Surgery, University of Heidelberg, Mannheim and Molecular Oncology of Solid Tumors, DKFZ, Heidelberg, Germany.
  • Fabian J; *Molecular Hepatology Alcohol Associated Diseases, Dept. of Medicine II, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
  • Weng HL; *Molecular Hepatology Alcohol Associated Diseases, Dept. of Medicine II, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
  • Teufel A; §§Klinik und Poliklinik für Innere Medizin I, Universitätsklinikum Regensburg, Regensburg, Germany.
  • Maass T; §§Klinik und Poliklinik für Innere Medizin I, Universitätsklinikum Regensburg, Regensburg, Germany.
  • Meyer C; *Molecular Hepatology Alcohol Associated Diseases, Dept. of Medicine II, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
  • Lehmann U; ║║Institute of Pathology, Medical School Hannover, Hannover, Germany.
  • Zhu C; ¶¶Department of Nephrology and Hypertension, Diabetes and Endocrinology, Otto-von-Guericke-University Magdeburg, Magdeburg, Germany.
  • Mertens PR; ¶¶Department of Nephrology and Hypertension, Diabetes and Endocrinology, Otto-von-Guericke-University Magdeburg, Magdeburg, Germany.
  • Gao CF; †Department of Laboratory Medicine, Eastern Hepatobiliary Hospital, Second Military Medical University, Shanghai, China.
  • Dooley S; *Molecular Hepatology Alcohol Associated Diseases, Dept. of Medicine II, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
  • Meindl-Beinker NM; *Molecular Hepatology Alcohol Associated Diseases, Dept. of Medicine II, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Clin Sci (Lond) ; 128(11): 761-74, 2015 Jun.
Article em En | MEDLINE | ID: mdl-25602745
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma Hepatocelular / Hepatócitos / Proliferação de Células / Proteína Smad7 / Hepatopatias / Neoplasias Hepáticas Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2015 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma Hepatocelular / Hepatócitos / Proliferação de Células / Proteína Smad7 / Hepatopatias / Neoplasias Hepáticas Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2015 Tipo de documento: Article