Dexrazoxane abrogates acute doxorubicin toxicity in marmoset ovary.

Salih, Sana M; Ringelstetter, Ashley K; Elsarrag, Mazin Z; Abbott, David H; Roti, Elon C Roti

Salih, Sana M; Ringelstetter, Ashley K; Elsarrag, Mazin Z; Abbott, David H; Roti, Elon C Roti.

Afiliação

Salih SM; Department of Obstetrics and Gynecology, Divisions of Reproductive Endocrinology and Infertility and Reproductive Sciences, University of Wisconsin, Madison, Wisconsin sanasalih5@gmail.com.
Ringelstetter AK; Department of Obstetrics and Gynecology, Divisions of Reproductive Endocrinology and Infertility and Reproductive Sciences, University of Wisconsin, Madison, Wisconsin.
Elsarrag MZ; Department of Obstetrics and Gynecology, Divisions of Reproductive Endocrinology and Infertility and Reproductive Sciences, University of Wisconsin, Madison, Wisconsin.
Abbott DH; Department of Obstetrics and Gynecology, Divisions of Reproductive Endocrinology and Infertility and Reproductive Sciences, University of Wisconsin, Madison, Wisconsin Wisconsin National Primate Research Center, University of Wisconsin, Madison, Wisconsin.
Roti EC; Department of Obstetrics and Gynecology, Divisions of Reproductive Endocrinology and Infertility and Reproductive Sciences, University of Wisconsin, Madison, Wisconsin.

Biol Reprod ; 92(3): 73, 2015 Mar.

Article em En | MEDLINE | ID: mdl-25609833

Assuntos

Antineoplásicos/efeitos adversos; Callithrix; Dexrazoxano/farmacologia; Doxorrubicina/efeitos adversos; Ovário/efeitos dos fármacos; Inibidores da Topoisomerase II/farmacologia; Animais; Antineoplásicos/farmacologia; Apoptose/efeitos dos fármacos; Caspase 9/metabolismo; Dano ao DNA/efeitos dos fármacos; Doxorrubicina/farmacologia; Feminino; Técnicas In Vitro; Modelos Animais; Ovário/metabolismo; Fosforilação; Proteínas Proto-Oncogênicas c-akt/metabolismo; Técnicas de Cultura de Tecidos

Palavras-chave

cancer survivor; dexrazoxane; doxorubicin; fertility; marmoset; ovary

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ovário / Callithrix / Doxorrubicina / Inibidores da Topoisomerase II / Dexrazoxano / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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