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Heart transplantation as salvage treatment of intractable infective endocarditis.
Aymami, Marie; Revest, Matthieu; Piau, Caroline; Chabanne, Céline; Le Gall, François; Lelong, Bernard; Verhoye, Jean-Philippe; Michelet, Christian; Tattevin, Pierre; Flécher, Erwan.
Afiliação
  • Aymami M; Department of Cardio-Thoracic and Vascular Surgery, France.
  • Revest M; Department of Infectious Disease and Intensive Care Unit, Pontchaillou University Hospital, Rennes, France; CIC Inserm 0203, Rennes-1 University, France.
  • Piau C; Department of Bacteriology, France.
  • Chabanne C; Department of Cardio-Thoracic and Vascular Surgery, France.
  • Le Gall F; Department of Pathology, Pontchaillou University Hospital, Rennes, France.
  • Lelong B; Department of Cardio-Thoracic and Vascular Surgery, France.
  • Verhoye JP; Department of Cardio-Thoracic and Vascular Surgery, France.
  • Michelet C; Department of Infectious Disease and Intensive Care Unit, Pontchaillou University Hospital, Rennes, France; CIC Inserm 0203, Rennes-1 University, France; Inserm CR 1085 IRSET, France.
  • Tattevin P; Department of Infectious Disease and Intensive Care Unit, Pontchaillou University Hospital, Rennes, France; CIC Inserm 0203, Rennes-1 University, France; Inserm U835, Rennes-1 University, France.
  • Flécher E; Department of Cardio-Thoracic and Vascular Surgery, France. Electronic address: pierre.tattevin@chu-rennes.fr.
Clin Microbiol Infect ; 21(4): 371.e1-4, 2015 Apr.
Article em En | MEDLINE | ID: mdl-25630459
This study reports six consecutive patients who underwent heart transplantation as salvage treatment for endocarditis (Duke criteria) with extensive perivalvular lesions and end-stage heart failure. The median age was 45 years (range, 24 to 64), and the aortic valve was affected in all patients. Pathogens were Staphylococcus aureus (n = 2), Streptococcus pneumoniae (n = 2), Streptococcus agalactiae (n = 1), or not documented (n = 1). All patients survived, with no relapse, after a median follow-up of 24.5 months. The 10 patients with heart transplantation for endocarditis previously reported also survived (median follow-up, 27.5 months). Heart transplantation may be considered as salvage treatment in selected patients with intractable infective endocarditis.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transplante de Coração / Terapia de Salvação / Endocardite Limite: Adolescent / Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2015 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transplante de Coração / Terapia de Salvação / Endocardite Limite: Adolescent / Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2015 Tipo de documento: Article