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Interleukin-18 is associated with protection against rhinovirus-induced colds and asthma exacerbations.
Jackson, David J; Glanville, Nicholas; Trujillo-Torralbo, Maria-Belen; Shamji, Betty W H; Del-Rosario, Jerico; Mallia, Patrick; Edwards, Matthew J; Walton, Ross P; Edwards, Michael R; Johnston, Sebastian L.
Afiliação
  • Jackson DJ; Airway Disease Infection Section, National Heart and Lung Institute, Imperial College Medical Research Council and Asthma UK Centre in Allergic Mechanisms of Asthma Imperial College Healthcare NHS Trust, London.
  • Glanville N; Airway Disease Infection Section, National Heart and Lung Institute, Imperial College Medical Research Council and Asthma UK Centre in Allergic Mechanisms of Asthma.
  • Trujillo-Torralbo MB; Airway Disease Infection Section, National Heart and Lung Institute, Imperial College Medical Research Council and Asthma UK Centre in Allergic Mechanisms of Asthma Imperial College Healthcare NHS Trust, London.
  • Shamji BW; Novartis Institute for Biomedical Research, Horsham, United Kingdom.
  • Del-Rosario J; Airway Disease Infection Section, National Heart and Lung Institute, Imperial College Medical Research Council and Asthma UK Centre in Allergic Mechanisms of Asthma Imperial College Healthcare NHS Trust, London.
  • Mallia P; Airway Disease Infection Section, National Heart and Lung Institute, Imperial College Medical Research Council and Asthma UK Centre in Allergic Mechanisms of Asthma Imperial College Healthcare NHS Trust, London.
  • Edwards MJ; Novartis Institute for Biomedical Research, Horsham, United Kingdom.
  • Walton RP; Airway Disease Infection Section, National Heart and Lung Institute, Imperial College Medical Research Council and Asthma UK Centre in Allergic Mechanisms of Asthma.
  • Edwards MR; Airway Disease Infection Section, National Heart and Lung Institute, Imperial College Medical Research Council and Asthma UK Centre in Allergic Mechanisms of Asthma.
  • Johnston SL; Airway Disease Infection Section, National Heart and Lung Institute, Imperial College Medical Research Council and Asthma UK Centre in Allergic Mechanisms of Asthma Imperial College Healthcare NHS Trust, London.
Clin Infect Dis ; 60(10): 1528-31, 2015 May 15.
Article em En | MEDLINE | ID: mdl-25645216
ABSTRACT
Rhinoviruses cause the common cold and exacerbations of asthma. Animal models of infection have identified a protective role for interleukin-18 (IL-18). Following experimental rhinovirus infection, we observed increased respiratory symptoms in healthy and asthmatic subjects with low nasal and bronchial IL-18 levels.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Asma / Rhinovirus / Resfriado Comum / Interleucina-18 Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Asma / Rhinovirus / Resfriado Comum / Interleucina-18 Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2015 Tipo de documento: Article