New therapeutics to modulate mitochondrial dynamics and mitophagy in cardiac diseases.
J Mol Med (Berl)
; 93(3): 279-87, 2015 Mar.
Article
em En
| MEDLINE
| ID: mdl-25652199
ABSTRACT
The processes that control the number and shape of the mitochondria (mitochondrial dynamics) and the removal of damaged mitochondria (mitophagy) have been the subject of intense research. Recent work indicates that these processes may contribute to the pathology associated with cardiac diseases. This review describes some of the key proteins that regulate these processes and their potential as therapeutic targets for cardiac diseases.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Cardiotônicos
/
Mitofagia
/
Dinâmica Mitocondrial
/
Cardiopatias
Limite:
Animals
/
Humans
Idioma:
En
Ano de publicação:
2015
Tipo de documento:
Article