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In vivo tracking of T cells in humans unveils decade-long survival and activity of genetically modified T memory stem cells.
Biasco, Luca; Scala, Serena; Basso Ricci, Luca; Dionisio, Francesca; Baricordi, Cristina; Calabria, Andrea; Giannelli, Stefania; Cieri, Nicoletta; Barzaghi, Federica; Pajno, Roberta; Al-Mousa, Hamoud; Scarselli, Alessia; Cancrini, Caterina; Bordignon, Claudio; Roncarolo, Maria Grazia; Montini, Eugenio; Bonini, Chiara; Aiuti, Alessandro.
Afiliação
  • Biasco L; San Raffaele Telethon Institute for Gene Therapy (TIGET), Division of Regenerative Medicine, Stem Cells, and Gene Therapy, Istituti di Ricovero e Cura a Carattere Scientifico (IRCCS) San Raffaele Scientific Institute, Milan 20132, Italy. luca.biasco@hsr.it a.aiuti@hsr.it.
  • Scala S; San Raffaele Telethon Institute for Gene Therapy (TIGET), Division of Regenerative Medicine, Stem Cells, and Gene Therapy, Istituti di Ricovero e Cura a Carattere Scientifico (IRCCS) San Raffaele Scientific Institute, Milan 20132, Italy. Vita-Salute San Raffaele University, Milan 20132, Italy.
  • Basso Ricci L; San Raffaele Telethon Institute for Gene Therapy (TIGET), Division of Regenerative Medicine, Stem Cells, and Gene Therapy, Istituti di Ricovero e Cura a Carattere Scientifico (IRCCS) San Raffaele Scientific Institute, Milan 20132, Italy.
  • Dionisio F; San Raffaele Telethon Institute for Gene Therapy (TIGET), Division of Regenerative Medicine, Stem Cells, and Gene Therapy, Istituti di Ricovero e Cura a Carattere Scientifico (IRCCS) San Raffaele Scientific Institute, Milan 20132, Italy.
  • Baricordi C; San Raffaele Telethon Institute for Gene Therapy (TIGET), Division of Regenerative Medicine, Stem Cells, and Gene Therapy, Istituti di Ricovero e Cura a Carattere Scientifico (IRCCS) San Raffaele Scientific Institute, Milan 20132, Italy.
  • Calabria A; San Raffaele Telethon Institute for Gene Therapy (TIGET), Division of Regenerative Medicine, Stem Cells, and Gene Therapy, Istituti di Ricovero e Cura a Carattere Scientifico (IRCCS) San Raffaele Scientific Institute, Milan 20132, Italy.
  • Giannelli S; San Raffaele Telethon Institute for Gene Therapy (TIGET), Division of Regenerative Medicine, Stem Cells, and Gene Therapy, Istituti di Ricovero e Cura a Carattere Scientifico (IRCCS) San Raffaele Scientific Institute, Milan 20132, Italy.
  • Cieri N; IRCCS San Raffaele Scientific Institute, Milan 20132, Italy.
  • Barzaghi F; Pediatric Immunohematology and Stem Cell Programme, IRCCS San Raffaele Scientific Institute, Milan 20132, Italy.
  • Pajno R; Pediatric Immunohematology and Stem Cell Programme, IRCCS San Raffaele Scientific Institute, Milan 20132, Italy.
  • Al-Mousa H; King Faisal Specialist Hospital & Research Centre, Riyadh 11211, Saudi Arabia.
  • Scarselli A; Department of Pediatrics, Ospedale Pediatrico Bambino Gesù and University of Rome "Tor Vergata," Rome 00165, Italy.
  • Cancrini C; Department of Pediatrics, Ospedale Pediatrico Bambino Gesù and University of Rome "Tor Vergata," Rome 00165, Italy.
  • Bordignon C; Vita-Salute San Raffaele University, Milan 20132, Italy.
  • Roncarolo MG; San Raffaele Telethon Institute for Gene Therapy (TIGET), Division of Regenerative Medicine, Stem Cells, and Gene Therapy, Istituti di Ricovero e Cura a Carattere Scientifico (IRCCS) San Raffaele Scientific Institute, Milan 20132, Italy. Vita-Salute San Raffaele University, Milan 20132, Italy.
  • Montini E; San Raffaele Telethon Institute for Gene Therapy (TIGET), Division of Regenerative Medicine, Stem Cells, and Gene Therapy, Istituti di Ricovero e Cura a Carattere Scientifico (IRCCS) San Raffaele Scientific Institute, Milan 20132, Italy.
  • Bonini C; IRCCS San Raffaele Scientific Institute, Milan 20132, Italy.
  • Aiuti A; Department of Pediatrics, Ospedale Pediatrico Bambino Gesù and University of Rome "Tor Vergata," Rome 00165, Italy. TIGET, Pediatric Immunohematology and Stem Cell Programme, San Raffaele Scientific Institute, Milan 20132, Italy. luca.biasco@hsr.it a.aiuti@hsr.it.
Sci Transl Med ; 7(273): 273ra13, 2015 Feb 04.
Article em En | MEDLINE | ID: mdl-25653219
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células-Tronco Hematopoéticas / Linfócitos T / Engenharia Genética / Rastreamento de Células / Memória Imunológica Tipo de estudo: Observational_studies Limite: Adult / Child / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células-Tronco Hematopoéticas / Linfócitos T / Engenharia Genética / Rastreamento de Células / Memória Imunológica Tipo de estudo: Observational_studies Limite: Adult / Child / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article