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Spin trapping: an essential tool for the study of diseases caused by oxidative stress.
Barriga-González, Germán; Olea-Azar, Claudio; Zuñiga-López, María C; Folch-Cano, Christian; Aguilera-Venegas, Benjamín; Porcal, Williams; González, Mercedes; Cerecetto, Hugo.
Afiliação
  • Cerecetto H; Universidad Andres Bello, Facultad de Ciencias Exactas, Departamento de Ciencias Quimicas, Avenida Republica 275, 8370146 Santiago, Chile. gbarriga@ciq.uchile.cl.
Curr Top Med Chem ; 15(5): 484-95, 2015.
Article em En | MEDLINE | ID: mdl-25658802
Electron spin resonance (ESR), called also electron paramagnetic resonance (EPR) together with the spin trapping technique, has allowed us to study and understand how free radicals are involved in various pathologies. In this review, the importance of spin trapping technique in the study of diseases such as cancer, diabetes, hypertension and parasitic diseases is discussed. In addition, advances in the use of this technique as therapeutic agents and other interesting applications as the immuno-spin trapping technique are reviewed.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Detecção de Spin / Doenças Neurodegenerativas / Diabetes Mellitus / Radicais Livres / Hipertensão / Neoplasias Tipo de estudo: Diagnostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Detecção de Spin / Doenças Neurodegenerativas / Diabetes Mellitus / Radicais Livres / Hipertensão / Neoplasias Tipo de estudo: Diagnostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article