Exclusion of the unfolded protein response in light-induced retinal degeneration in the canine T4R RHO model of autosomal dominant retinitis pigmentosa.

Marsili, Stefania; Genini, Sem; Sudharsan, Raghavi; Gingrich, Jeremy; Aguirre, Gustavo D; Beltran, William A

Marsili, Stefania; Genini, Sem; Sudharsan, Raghavi; Gingrich, Jeremy; Aguirre, Gustavo D; Beltran, William A.

Afiliação

Marsili S; Section of Ophthalmology, Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, 19104, United States of America.
Genini S; Section of Ophthalmology, Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, 19104, United States of America.
Sudharsan R; Section of Ophthalmology, Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, 19104, United States of America.
Gingrich J; Section of Ophthalmology, Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, 19104, United States of America.
Aguirre GD; Section of Ophthalmology, Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, 19104, United States of America.
Beltran WA; Section of Ophthalmology, Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, 19104, United States of America.

PLoS One ; 10(2): e0115723, 2015.

Article em En | MEDLINE | ID: mdl-25695253

Assuntos

Luz/efeitos adversos; Retina/metabolismo; Retina/patologia; Retinose Pigmentar/metabolismo; Resposta a Proteínas não Dobradas/fisiologia; Animais; Morte Celular/genética; Morte Celular/fisiologia; Cães; Marcação In Situ das Extremidades Cortadas; Retinose Pigmentar/patologia; Rodopsina/genética; Rodopsina/metabolismo; Resposta a Proteínas não Dobradas/genética

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Retina / Retinose Pigmentar / Resposta a Proteínas não Dobradas / Luz Limite: Animals Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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