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Tuning cytokine receptor signaling by re-orienting dimer geometry with surrogate ligands.
Moraga, Ignacio; Wernig, Gerlinde; Wilmes, Stephan; Gryshkova, Vitalina; Richter, Christian P; Hong, Wan-Jen; Sinha, Rahul; Guo, Feng; Fabionar, Hyna; Wehrman, Tom S; Krutzik, Peter; Demharter, Samuel; Plo, Isabelle; Weissman, Irving L; Minary, Peter; Majeti, Ravindra; Constantinescu, Stefan N; Piehler, Jacob; Garcia, K Christopher.
Afiliação
  • Moraga I; Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA 94305-5345, USA; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA 94305-5345, USA.
  • Wernig G; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305-5345, USA; Department of Pathology, Division of Hematopathology, Stanford University School of Medicine, Stanford, CA 94305-5345, USA.
  • Wilmes S; Division of Biophysics, Department of Biology, University of Osnabrück, 49076 Osnabrück, Germany.
  • Gryshkova V; Ludwig Institute for Cancer Research and de Duve Institute, Université catholique de Louvain, 1200 Brussels, Belgium.
  • Richter CP; Division of Biophysics, Department of Biology, University of Osnabrück, 49076 Osnabrück, Germany.
  • Hong WJ; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305-5345, USA; Department of Internal Medicine, Division of Hematology, Stanford University School of Medicine, Stanford, CA 94305-5345, USA.
  • Sinha R; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305-5345, USA.
  • Guo F; Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA 94305-5345, USA; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA 94305-5345, USA.
  • Fabionar H; DiscoveRx, 42501 Albrae Street, Fremont, CA 94538, USA.
  • Wehrman TS; Primity Bio, 3350 Scott Boulevard, Suite 6101, Santa Clara, CA 95054, USA.
  • Krutzik P; Primity Bio, 3350 Scott Boulevard, Suite 6101, Santa Clara, CA 95054, USA.
  • Demharter S; Department of Computational Biology, Department of Computer Science, University of Oxford, Oxford OX1 3QD, UK.
  • Plo I; Institut Gustave Roussy, INSERM U1009, 94805 Villejuif, France.
  • Weissman IL; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305-5345, USA.
  • Minary P; Department of Computational Biology, Department of Computer Science, University of Oxford, Oxford OX1 3QD, UK.
  • Majeti R; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305-5345, USA; Department of Internal Medicine, Division of Hematology, Stanford University School of Medicine, Stanford, CA 94305-5345, USA.
  • Constantinescu SN; Ludwig Institute for Cancer Research and de Duve Institute, Université catholique de Louvain, 1200 Brussels, Belgium.
  • Piehler J; Division of Biophysics, Department of Biology, University of Osnabrück, 49076 Osnabrück, Germany.
  • Garcia KC; Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA 94305-5345, USA; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA 94305-5345, USA. Electronic address: kcgarcia@stanford.edu.
Cell ; 160(6): 1196-208, 2015 Mar 12.
Article em En | MEDLINE | ID: mdl-25728669
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Receptores da Eritropoetina Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Receptores da Eritropoetina Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article