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[Complete response in a case of anastomotic recurrence of rectal cancer treated with S-1 monotherapy].
Kabashima, Akira; Kitagawa, Dai; Nakamura, Toshihiko; Kondo, Naoko; Teramoto, Seiichi; Saito, Genkichi; Funahashi, Tomoru; Adachi, Eisuke; Ikeda, Yoichi.
Afiliação
  • Kabashima A; Dept. of Surgery, Kyushu Central Hospital of the Mutual Aid Association of Public School Teachers.
Gan To Kagaku Ryoho ; 41(12): 1716-8, 2014 Nov.
Article em Ja | MEDLINE | ID: mdl-25731306
A 63-year-old woman underwent a low anterior resection for rectal cancer in 2002.A n anastomotic recurrence was diagnosed in July 2011.S he rejected the possibility of colostomy as radical surgery.Chemotherapy consisting of capecitabine+ oxaliplatin (XELOX) or folinic acid, fluorouracil, and oxaliplatin (FOLFOX6) + bevacizumab were not possible because of high costs. In view of the lower costs and the potential for ambulation, S-1 monotherapy was started. After 3 months, a reduction in the recurrent lesion was observed.After 19 months, the recurrent lesion revealed a scar, which was judged by biopsy to be Group 1.We had achieved a pathological complete response (CR).The standard treatment for recurrent colon cancer is surgical resection or multidrug chemotherapy. However, in view of a patient's quality of life (QOL), S-1 monotherapy may be considered as a potential therapy.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ácido Oxônico / Neoplasias Retais / Tegafur / Recidiva Local de Neoplasia / Antimetabólitos Antineoplásicos Limite: Female / Humans / Middle aged Idioma: Ja Ano de publicação: 2014 Tipo de documento: Article
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ácido Oxônico / Neoplasias Retais / Tegafur / Recidiva Local de Neoplasia / Antimetabólitos Antineoplásicos Limite: Female / Humans / Middle aged Idioma: Ja Ano de publicação: 2014 Tipo de documento: Article