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Two-dimensional IR spectroscopy of the anti-HIV agent KP1212 reveals protonated and neutral tautomers that influence pH-dependent mutagenicity.
Peng, Chunte Sam; Fedeles, Bogdan I; Singh, Vipender; Li, Deyu; Amariuta, Tiffany; Essigmann, John M; Tokmakoff, Andrei.
Afiliação
  • Peng CS; Departments of Chemistry and.
  • Fedeles BI; Departments of Chemistry and Biological Engineering and Center for Environmental Health Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139; and.
  • Singh V; Departments of Chemistry and Biological Engineering and Center for Environmental Health Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139; and.
  • Li D; Departments of Chemistry and Biological Engineering and Center for Environmental Health Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139; and.
  • Amariuta T; Biological Engineering and.
  • Essigmann JM; Departments of Chemistry and Biological Engineering and Center for Environmental Health Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139; and tokmakoff@uchicago.edu jessig@mit.edu.
  • Tokmakoff A; Department of Chemistry, Institute for Biophysical Dynamics, and James Franck Institute, The University of Chicago, Chicago, IL 60637 tokmakoff@uchicago.edu jessig@mit.edu.
Proc Natl Acad Sci U S A ; 112(11): 3229-34, 2015 Mar 17.
Article em En | MEDLINE | ID: mdl-25733867
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Prótons / Fármacos Anti-HIV / Desoxicitidina Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Prótons / Fármacos Anti-HIV / Desoxicitidina Idioma: En Ano de publicação: 2015 Tipo de documento: Article