Unlike catalyzing error-free bypass of 8-oxodGuo, DNA polymerase &#955; is responsible for a significant part of Fapy·dG-induced G â T mutations in human cells.

Pande, Paritosh; Haraguchi, Kazuhiro; Jiang, Yu-Lin; Greenberg, Marc M; Basu, Ashis K

Unlike catalyzing error-free bypass of 8-oxodGuo, DNA polymerase λ is responsible for a significant part of Fapy·dG-induced G â T mutations in human cells.

Pande, Paritosh; Haraguchi, Kazuhiro; Jiang, Yu-Lin; Greenberg, Marc M; Basu, Ashis K.

Afiliação

Pande P; Department of Chemistry, University of Connecticut, Storrs, Connecticut 06269, United States.
Haraguchi K; Department of Chemistry, Johns Hopkins University, Baltimore, Maryland 21218, United States.
Jiang YL; Department of Chemistry, Johns Hopkins University, Baltimore, Maryland 21218, United States.
Greenberg MM; Department of Chemistry, Johns Hopkins University, Baltimore, Maryland 21218, United States.
Basu AK; Department of Chemistry, University of Connecticut, Storrs, Connecticut 06269, United States.

Biochemistry ; 54(10): 1859-62, 2015 Mar 17.

Article em En | MEDLINE | ID: mdl-25741586

Assuntos

DNA Polimerase beta/química; DNA/química; Guanosina Trifosfato/análogos & derivados; Mutação Puntual; Nucleotídeos de Timina/química; Catálise; DNA/biossíntese; DNA/genética; DNA Polimerase beta/metabolismo; Guanosina Trifosfato/química; Guanosina Trifosfato/genética; Guanosina Trifosfato/metabolismo; Humanos; Nucleotídeos de Timina/genética; Nucleotídeos de Timina/metabolismo

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Nucleotídeos de Timina / DNA / Mutação Puntual / DNA Polimerase beta / Guanosina Trifosfato Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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