Higher risk of developing sudden sensorineural hearing loss in patients with chronic otitis media.
JAMA Otolaryngol Head Neck Surg
; 141(5): 429-35, 2015 May 01.
Article
em En
| MEDLINE
| ID: mdl-25741670
ABSTRACT
IMPORTANCE Several sources have suggested an association between chronic sensory hearing impairment and chronic otitis media (COM). However, to our knowledge, no studies have evaluated the risk of sudden sensorineural hearing loss (SSNHL) in patients with COM (COM-positive). OBJECTIVE:
To examine the risk of developing SSNHL in COM-positive patients. DESIGN, SETTING, ANDPARTICIPANTS:
This was a retrospective cohort study; we compared 10â¯248 patients with newly diagnosed COM from January 1, 2001, through December 31, 2008, with 30â¯744 age- and sex-matched controls using data from Taiwan's National Health Insurance Research Database.METHODS:
We followed each patient and evaluated the incidence of SSNHL. MAIN OUTCOMES ANDMEASURES:
The incidence of SSNHL at the end of 2011.RESULTS:
The incidence of SSNHL was 3 times higher in the COM-positive cohort than in the COM-negative cohort (14.47 vs 4.83 per 10â¯000 person-years). Cox proportional hazard regressions showed that the adjusted hazard ratio (AHR) was 3.02 (95% CI, 2.30-3.98). A stratified analysis showed that the highest risk of developing SSNHL was in the first follow-up year (incidence rate ratio [IRR], 3.87; 95% CI, 1.93-7.79). Thereafter, the risk declined during years 1 to 5 and then peaked (IRR, 3.01; 95% CI, 1.89-4.79). Patients who needed surgery had a higher incidence of SSNHL (AHR, 2.69; 95% CI, 1.62-4.48) compared with patients who needed only medication and observation. CONCLUSIONS AND RELEVANCE Chronic otitis media was significantly associated with a higher risk of developing SSNHL.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Otite Média
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Perda Auditiva Súbita
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Perda Auditiva Neurossensorial
Tipo de estudo:
Etiology_studies
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Incidence_studies
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Observational_studies
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Prognostic_studies
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Risk_factors_studies
Limite:
Adolescent
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Adult
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Aged
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Child
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Child, preschool
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Female
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Humans
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Infant
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Male
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Middle aged
País/Região como assunto:
Asia
Idioma:
En
Ano de publicação:
2015
Tipo de documento:
Article