Death following traumatic brain injury in Drosophila is associated with intestinal barrier dysfunction.

Katzenberger, Rebeccah J; Chtarbanova, Stanislava; Rimkus, Stacey A; Fischer, Julie A; Kaur, Gulpreet; Seppala, Jocelyn M; Swanson, Laura C; Zajac, Jocelyn E; Ganetzky, Barry; Wassarman, David A

Katzenberger, Rebeccah J; Chtarbanova, Stanislava; Rimkus, Stacey A; Fischer, Julie A; Kaur, Gulpreet; Seppala, Jocelyn M; Swanson, Laura C; Zajac, Jocelyn E; Ganetzky, Barry; Wassarman, David A.

Afiliação

Katzenberger RJ; Department of Cell and Regenerative Biology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, United States.
Chtarbanova S; Laboratory of Genetics, University of Wisconsin-Madison, Madison, United States.
Rimkus SA; Department of Cell and Regenerative Biology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, United States.
Fischer JA; Department of Cell and Regenerative Biology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, United States.
Kaur G; Department of Cell and Regenerative Biology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, United States.
Seppala JM; Department of Cell and Regenerative Biology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, United States.
Swanson LC; Department of Cell and Regenerative Biology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, United States.
Zajac JE; Department of Cell and Regenerative Biology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, United States.
Ganetzky B; Laboratory of Genetics, University of Wisconsin-Madison, Madison, United States.
Wassarman DA; Department of Cell and Regenerative Biology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, United States.

Elife ; 42015 Mar 05.

Article em En | MEDLINE | ID: mdl-25742603

Assuntos

Lesões Encefálicas/genética; Proteínas de Drosophila/genética; Mucosa Intestinal/metabolismo; Polimorfismo de Nucleotídeo Único; Animais; Animais Recém-Nascidos; Carga Bacteriana; Barreira Hematoaquosa/metabolismo; Barreira Hematoaquosa/fisiopatologia; Barreira Hematoencefálica/metabolismo; Barreira Hematoencefálica/fisiopatologia; Barreira Hematorretiniana/metabolismo; Barreira Hematorretiniana/fisiopatologia; Lesões Encefálicas/metabolismo; Lesões Encefálicas/mortalidade; Proteínas de Ligação a DNA/genética; Proteínas de Ligação a DNA/metabolismo; Modelos Animais de Doenças; Proteínas de Drosophila/metabolismo; Drosophila melanogaster/genética; Drosophila melanogaster/metabolismo; Expressão Gênica; Glucose/administração & dosagem; Glucose/metabolismo; Glucose/farmacologia; Hemolinfa/metabolismo; Hemolinfa/microbiologia; Humanos; Intestinos/efeitos dos fármacos; Intestinos/fisiopatologia; Reação em Cadeia da Polimerase Via Transcriptase Reversa; Fatores de Risco; Taxa de Sobrevida; Fatores de Tempo; Fatores de Transcrição/genética; Fatores de Transcrição/metabolismo

Palavras-chave

D. melanogaster; bloodbrain barrier; chromosomes; genes; glucose homeostasis; grainyhead; hexosamine biosynthesis pathway; innate immune response; neuroscience; septate junction

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Lesões Encefálicas / Polimorfismo de Nucleotídeo Único / Proteínas de Drosophila / Mucosa Intestinal Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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