N-acetylcysteine treats intravenous amiodarone induced liver injury.
World J Gastroenterol
; 21(9): 2816-9, 2015 Mar 07.
Article
em En
| MEDLINE
| ID: mdl-25759554
ABSTRACT
We report a case of intravenous (IV) amiodarone drug induced liver injury (DILI). The patient received IV N-acetylcysteine (NAC) which resulted in a rapid improvement in liver enzymes. While the specific mechanisms for the pathogenesis of IV amiodarone DILI and the therapeutic action of IV NAC are both unknown, this case strongly implies at least some commonality. Because IV amiodarone is indicated for the treatment of serious cardiac arrhythmias in an intensive care unit setting, some degree of ischemic hepatitis is likely a cofactor in most cases.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Acetilcisteína
/
Doença Hepática Induzida por Substâncias e Drogas
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Amiodarona
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Fígado
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Antiarrítmicos
/
Antioxidantes
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
Limite:
Aged
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Female
/
Humans
Idioma:
En
Ano de publicação:
2015
Tipo de documento:
Article