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The cholesterol biosynthesis enzyme oxidosqualene cyclase is a new target to impair tumour angiogenesis and metastasis dissemination.
Maione, Federica; Oliaro-Bosso, Simonetta; Meda, Claudia; Di Nicolantonio, Federica; Bussolino, Federico; Balliano, Gianni; Viola, Franca; Giraudo, Enrico.
Afiliação
  • Maione F; 1] Laboratory of Transgenic Mouse Models, Candiolo Cancer Institute - FPO, IRCCS, Str prov 142 Km 3.95. 10060, Candiolo, Italy [2] Department of Science and Drug Technology, University of Turin, Via P. Giuria 9, 10125 Turin, Italy.
  • Oliaro-Bosso S; 1] Laboratory of Biochemistry and Molecular Biology, University of Turin, Via P. Giuria 9, 10125, Turin, Italy [2] Department of Science and Drug Technology, University of Turin, Via P. Giuria 9, 10125 Turin, Italy.
  • Meda C; 1] Laboratory of Transgenic Mouse Models, Candiolo Cancer Institute - FPO, IRCCS, Str prov 142 Km 3.95. 10060, Candiolo, Italy [2] Department of Science and Drug Technology, University of Turin, Via P. Giuria 9, 10125 Turin, Italy.
  • Di Nicolantonio F; 1] Laboratory of Cancer Epigenetics, Candiolo Cancer Institute - FPO, IRCCS, Str prov 142 Km 3.95. 10060, Candiolo, Italy [2] Department of Oncology, University of Turin, 10100, Turin, Italy.
  • Bussolino F; 1] Laboratory of Vascular Oncology, Candiolo Cancer Institute, IRCCS, Str prov 142 Km 3.95. 10060, Candiolo, Italy [2] Department of Oncology, University of Turin, 10100, Turin, Italy.
  • Balliano G; 1] Laboratory of Biochemistry and Molecular Biology, University of Turin, Via P. Giuria 9, 10125, Turin, Italy [2] Department of Science and Drug Technology, University of Turin, Via P. Giuria 9, 10125 Turin, Italy.
  • Viola F; 1] Laboratory of Biochemistry and Molecular Biology, University of Turin, Via P. Giuria 9, 10125, Turin, Italy [2] Department of Science and Drug Technology, University of Turin, Via P. Giuria 9, 10125 Turin, Italy.
  • Giraudo E; 1] Laboratory of Transgenic Mouse Models, Candiolo Cancer Institute - FPO, IRCCS, Str prov 142 Km 3.95. 10060, Candiolo, Italy [2] Department of Science and Drug Technology, University of Turin, Via P. Giuria 9, 10125 Turin, Italy.
Sci Rep ; 5: 9054, 2015 Mar 12.
Article em En | MEDLINE | ID: mdl-25761781
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Colesterol / Transferases Intramoleculares / Neoplasias / Neovascularização Patológica Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Colesterol / Transferases Intramoleculares / Neoplasias / Neovascularização Patológica Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2015 Tipo de documento: Article