Downregulated expression of miR-155, miR-17, and miR-181b, and upregulated expression of activation-induced cytidine deaminase and interferon-&#945; in PBMCs from patients with SLE.

Kaga, Hagime; Komatsuda, Atsushi; Omokawa, Ayumi; Ito, Mitsugu; Teshima, Kazuaki; Tagawa, Hiroyuki; Sawada, Kenichi; Wakui, Hideki

Downregulated expression of miR-155, miR-17, and miR-181b, and upregulated expression of activation-induced cytidine deaminase and interferon-α in PBMCs from patients with SLE.

Kaga, Hagime; Komatsuda, Atsushi; Omokawa, Ayumi; Ito, Mitsugu; Teshima, Kazuaki; Tagawa, Hiroyuki; Sawada, Kenichi; Wakui, Hideki.

Afiliação

Kaga H; a Department of Hematology , Nephrology, and Rheumatology, Akita University Graduate School of Medicine , Akita , Japan.
Komatsuda A; a Department of Hematology , Nephrology, and Rheumatology, Akita University Graduate School of Medicine , Akita , Japan.
Omokawa A; a Department of Hematology , Nephrology, and Rheumatology, Akita University Graduate School of Medicine , Akita , Japan.
Ito M; a Department of Hematology , Nephrology, and Rheumatology, Akita University Graduate School of Medicine , Akita , Japan.
Teshima K; a Department of Hematology , Nephrology, and Rheumatology, Akita University Graduate School of Medicine , Akita , Japan.
Tagawa H; a Department of Hematology , Nephrology, and Rheumatology, Akita University Graduate School of Medicine , Akita , Japan.
Sawada K; a Department of Hematology , Nephrology, and Rheumatology, Akita University Graduate School of Medicine , Akita , Japan.
Wakui H; a Department of Hematology , Nephrology, and Rheumatology, Akita University Graduate School of Medicine , Akita , Japan.

Mod Rheumatol ; 25(6): 865-70, 2015.

Article em En | MEDLINE | ID: mdl-25775145

Assuntos

Citidina Desaminase/genética; Regulação para Baixo; Interferon-alfa/genética; Lúpus Eritematoso Sistêmico/genética; MicroRNAs/genética; Regulação para Cima; Adolescente; Adulto; Idoso; Citidina Desaminase/metabolismo; Feminino; Humanos; Interferon-alfa/metabolismo; Leucócitos Mononucleares/metabolismo; Lúpus Eritematoso Sistêmico/metabolismo; Masculino; MicroRNAs/metabolismo; Pessoa de Meia-Idade; RNA Mensageiro/metabolismo; Adulto Jovem

Palavras-chave

Activation-induced cytidine deaminase; Interferon-α; MicroRNAs; Peripheral blood mononuclear cells; Systemic lupus erythematosus

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Regulação para Baixo / Regulação para Cima / Interferon-alfa / Citidina Desaminase / MicroRNAs / Lúpus Eritematoso Sistêmico Limite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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