CD5 helps aspiring regulatory T cells ward off unwelcome cytokine advances.

Palin, Amy C; Love, Paul E

Palin, Amy C; Love, Paul E.

Afiliação

Palin AC; Eunice Kennedy Shriver, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.
Love PE; Eunice Kennedy Shriver, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA. Electronic address: lovep@mail.nih.gov.

Immunity ; 42(3): 395-6, 2015 Mar 17.

Article em En | MEDLINE | ID: mdl-25786168

ABSTRACT

ABSTRACT

The role of co-receptor molecules in the generation of inducible regulatory T cells (iTregs) remains incompletely defined. In this issue of Immunity, Henderson et al. (2015) show that CD5 regulates iTreg cell induction by rendering emerging iTreg cells refractory to signals mediated by effector-differentiating cytokines.

Assuntos

Autoantígenos/imunologia; Antígenos CD5/imunologia; Linfócitos T Reguladores/metabolismo; Animais

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Autoantígenos / Linfócitos T Reguladores / Antígenos CD5 Limite: Animals Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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