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The possible role of glutathione-S-transferase activity in diabetic nephropathy.
Tesauro, M; Nisticò, S; Noce, A; Tarantino, A; Marrone, G; Costa, A; Rovella, V; Di Cola, G; Campia, U; Lauro, D; Cardillo, C; Di Daniele, N.
Afiliação
  • Tesauro M; Department of Systems Medicine, Division of Hypertension and Nephrology, University of Rome "Tor Vergata", Rome, Italy.
  • Nisticò S; Department of Health Sciences, University of Catanzaro 'Magna Graecia', Catanzaro, Italy steven.nistico@gmail.com.
  • Noce A; Department of Systems Medicine, Division of Hypertension and Nephrology, University of Rome "Tor Vergata", Rome, Italy.
  • Tarantino A; Department of Systems Medicine, Division of Hypertension and Nephrology, University of Rome "Tor Vergata", Rome, Italy.
  • Marrone G; Department of Systems Medicine, Division of Hypertension and Nephrology, University of Rome "Tor Vergata", Rome, Italy.
  • Costa A; Center of Integrated Research, Campus Bio-Medico University of Rome, Rome, Italy.
  • Rovella V; Department of Systems Medicine, Division of Hypertension and Nephrology, University of Rome "Tor Vergata", Rome, Italy.
  • Di Cola G; Department of Systems Medicine, Division of Hypertension and Nephrology, University of Rome "Tor Vergata", Rome, Italy.
  • Campia U; MedStar Cardiovascular Research Network Washington, DC, USA.
  • Lauro D; Endocrinology Unit, University of Rome "Tor Vergata", Rome, Italy.
  • Cardillo C; Internal Medicine, Catholic University, Rome, Italy.
  • Di Daniele N; Department of Systems Medicine, Division of Hypertension and Nephrology, University of Rome "Tor Vergata", Rome, Italy.
Int J Immunopathol Pharmacol ; 28(1): 129-33, 2015 Mar.
Article em En | MEDLINE | ID: mdl-25816416
ABSTRACT
The most common cause of end stage renal disease is diabetic nephropathy. An early diagnosis may allow an intervention to slow down disease progression. Recently, it has been hypothesized that glutathione-S-transferase (GST) activity may be a marker of severity of chronic kidney disease. In particular, a lower GST activity is present in healthy subjects compared to patients with nephropathy. In the present review we illustrate the scientific evidence underlying the possible role of GST activity in the development of diabetic nephropathy and we analyze its usefulness as a possible early biomarker of this diabetic complication.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Complicações do Diabetes / Nefropatias Diabéticas / Glutationa Transferase Tipo de estudo: Screening_studies Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Complicações do Diabetes / Nefropatias Diabéticas / Glutationa Transferase Tipo de estudo: Screening_studies Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article