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Auranofin exerts broad-spectrum bactericidal activities by targeting thiol-redox homeostasis.
Harbut, Michael B; Vilchèze, Catherine; Luo, Xiaozhou; Hensler, Mary E; Guo, Hui; Yang, Baiyuan; Chatterjee, Arnab K; Nizet, Victor; Jacobs, William R; Schultz, Peter G; Wang, Feng.
Afiliação
  • Harbut MB; California Institute for Biomedical Research, La Jolla, CA 92037;
  • Vilchèze C; Howard Hughes Medical Institute and Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461;
  • Luo X; Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA 92037; and.
  • Hensler ME; Department of Pediatrics and Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California at San Diego, La Jolla, CA 92093.
  • Guo H; California Institute for Biomedical Research, La Jolla, CA 92037;
  • Yang B; California Institute for Biomedical Research, La Jolla, CA 92037;
  • Chatterjee AK; California Institute for Biomedical Research, La Jolla, CA 92037;
  • Nizet V; Department of Pediatrics and Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California at San Diego, La Jolla, CA 92093.
  • Jacobs WR; Howard Hughes Medical Institute and Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461;
  • Schultz PG; California Institute for Biomedical Research, La Jolla, CA 92037; Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA 92037; and schultz@scripps.edu fwang@calibr.org.
  • Wang F; California Institute for Biomedical Research, La Jolla, CA 92037; schultz@scripps.edu fwang@calibr.org.
Proc Natl Acad Sci U S A ; 112(14): 4453-8, 2015 Apr 07.
Article em En | MEDLINE | ID: mdl-25831516

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Compostos de Sulfidrila / Auranofina / Antibacterianos Limite: Animals Idioma: En Ano de publicação: 2015 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Compostos de Sulfidrila / Auranofina / Antibacterianos Limite: Animals Idioma: En Ano de publicação: 2015 Tipo de documento: Article