Intranasal delivery of bone marrow stromal cells to spinal cord lesions.

Ninomiya, Koshi; Iwatsuki, Koichi; Ohnishi, Yu-ichiro; Ohkawa, Toshika; Yoshimine, Toshiki

Ninomiya, Koshi; Iwatsuki, Koichi; Ohnishi, Yu-ichiro; Ohkawa, Toshika; Yoshimine, Toshiki.

Afiliação

Ninomiya K; Department of Neurosurgery, Osaka University Graduate School of Medicine, Suita City, Osaka, Japan.
Iwatsuki K; Department of Neurosurgery, Osaka University Graduate School of Medicine, Suita City, Osaka, Japan.
Ohnishi Y; Department of Neurosurgery, Osaka University Graduate School of Medicine, Suita City, Osaka, Japan.
Ohkawa T; Department of Neurosurgery, Osaka University Graduate School of Medicine, Suita City, Osaka, Japan.
Yoshimine T; Department of Neurosurgery, Osaka University Graduate School of Medicine, Suita City, Osaka, Japan.

J Neurosurg Spine ; 23(1): 111-9, 2015 Jul.

Article em En | MEDLINE | ID: mdl-25840039

Assuntos

Transplante de Medula Óssea/métodos; Transplante de Células-Tronco Mesenquimais/métodos; Doenças da Medula Espinal/terapia; Administração Intranasal; Animais; Movimento Celular; Ensaio de Imunoadsorção Enzimática; Imuno-Histoquímica; Masculino; Ratos; Ratos Sprague-Dawley; Recuperação de Função Fisiológica

Palavras-chave

BBB = Basso-Beattie-Bresnahan; BDNF = brain-derived neurotrophic factor; BMSC = bone marrow stromal cell; DAPI = 4',6-diamidino-2-phenylindole; DMEM = Dulbecco modified Eagle medium; EGFP = enhanced green fluorescent protein; MSC = mesenchymal stem cell; NGF = nerve growth factor; PBS = phosphate-buffered saline; SCI = spinal cord injury; SEM = standard error of the mean; bone marrow stromal cells; i.n. = intranasal; i.t. = intrathecal; intranasal delivery; spinal cord injury

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças da Medula Espinal / Transplante de Medula Óssea / Transplante de Células-Tronco Mesenquimais Limite: Animals Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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