A retrospective study of factors which determine a negative blood culture in Cambodian children diagnosed with enteric fever.
Paediatr Int Child Health
; 36(2): 118-21, 2016 May.
Article
em En
| MEDLINE
| ID: mdl-25845519
ABSTRACT
BACKGROUND:
Blood cultures are used to confirm a diagnosis of enteric fever but reported sensitivities can be as low as 40%.AIMS:
To determine the factors associated with a negative blood culture in Cambodian children with suspected enteric fever.METHODS:
In a retrospective study of hospitalised Cambodian children given a discharge diagnosis of enteric fever, the following factors associated with a negative blood culture were analysed age, blood culture volume, prior antibiotic therapy, duration of illness and disease severity.RESULTS:
In 227 hospitalised Cambodian children with a discharge diagnosis of enteric fever, it was confirmed in 70% by a positive blood culture. There was no association between a negative blood culture and younger age, lower blood volumes for culture, prior antibiotic therapy, a late presentation or milder disease.CONCLUSIONS:
Although blood culture sensitivity was higher than expected, alternative simple, rapid and sensitive tests are needed for diagnosing enteric fever.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Salmonella typhi
/
Febre Tifoide
/
Hemocultura
Tipo de estudo:
Diagnostic_studies
/
Observational_studies
/
Risk_factors_studies
Limite:
Child
/
Child, preschool
/
Female
/
Humans
/
Male
País/Região como assunto:
Asia
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article