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Mechanism of action studies of lomaiviticin A and the monomeric lomaiviticin aglycon. Selective and potent activity toward DNA double-strand break repair-deficient cell lines.
Colis, Laureen C; Hegan, Denise C; Kaneko, Miho; Glazer, Peter M; Herzon, Seth B.
Afiliação
  • Colis LC; †Department of Chemistry, Yale University, New Haven, Connecticut 06520, United States.
  • Hegan DC; ‡Departments of Therapeutic Radiology and Genetics, Yale School of Medicine, New Haven, Connecticut 06520, United States.
  • Kaneko M; †Department of Chemistry, Yale University, New Haven, Connecticut 06520, United States.
  • Glazer PM; ‡Departments of Therapeutic Radiology and Genetics, Yale School of Medicine, New Haven, Connecticut 06520, United States.
  • Herzon SB; †Department of Chemistry, Yale University, New Haven, Connecticut 06520, United States.
J Am Chem Soc ; 137(17): 5741-7, 2015 May 06.
Article em En | MEDLINE | ID: mdl-25849366
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteína BRCA2 / PTEN Fosfo-Hidrolase / Quebras de DNA de Cadeia Dupla / Fluorenos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteína BRCA2 / PTEN Fosfo-Hidrolase / Quebras de DNA de Cadeia Dupla / Fluorenos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article