Tobacco smoking strongly modifies the association of prothrombin G20210A with undetermined stroke: consecutive survivors and population-based controls.

Krajcoviechova, A; Wohlfahrt, P; Mayer, O; Vanek, J; Hajkova, J; Hlinovsky, D; Kvasnicka, T; Tremblay, J; Hamet, P; Filipovsky, J; Kvasnicka, J; Cifkova, R

Krajcoviechova, A; Wohlfahrt, P; Mayer, O; Vanek, J; Hajkova, J; Hlinovsky, D; Kvasnicka, T; Tremblay, J; Hamet, P; Filipovsky, J; Kvasnicka, J; Cifkova, R.

Afiliação

Krajcoviechova A; Center for Cardiovascular Prevention, First Medical School of Charles University in Prague and Thomayer Hospital, Czech Republic. Electronic address: alena.krajcoviechova@ftn.cz.
Wohlfahrt P; Center for Cardiovascular Prevention, First Medical School of Charles University in Prague and Thomayer Hospital, Czech Republic.
Mayer O; 2nd Department of Internal Medicine, Charles University Medical Faculty and Teaching Hospital, Pilsen, Czech Republic.
Vanek J; 2nd Department of Internal Medicine, Charles University Medical Faculty and Teaching Hospital, Pilsen, Czech Republic.
Hajkova J; Central Laboratory for Hematology and Thrombotic Centre, First Medical School of Charles University in Prague and General Teaching Hospital, Prague, Czech Republic.
Hlinovsky D; Department of Neurology of Thomayer Hospital in Prague, Czech Republic.
Kvasnicka T; Central Laboratory for Hematology and Thrombotic Centre, First Medical School of Charles University in Prague and General Teaching Hospital, Prague, Czech Republic.
Tremblay J; Montreal University Hospital Research Center, CRCHUM, Montreal, Canada.
Hamet P; Montreal University Hospital Research Center, CRCHUM, Montreal, Canada.
Filipovsky J; 2nd Department of Internal Medicine, Charles University Medical Faculty and Teaching Hospital, Pilsen, Czech Republic.
Kvasnicka J; Central Laboratory for Hematology and Thrombotic Centre, First Medical School of Charles University in Prague and General Teaching Hospital, Prague, Czech Republic.
Cifkova R; Center for Cardiovascular Prevention, First Medical School of Charles University in Prague and Thomayer Hospital, Czech Republic.

Atherosclerosis ; 240(2): 446-52, 2015 Jun.

Article em En | MEDLINE | ID: mdl-25897999

Assuntos

Polimorfismo Genético; Protrombina/genética; Fumar/efeitos adversos; Acidente Vascular Cerebral/genética; Trombofilia/genética; Adolescente; Adulto; Idoso; Idoso de 80 Anos ou mais; Isquemia Encefálica/diagnóstico; Isquemia Encefálica/epidemiologia; Isquemia Encefálica/genética; Estudos de Casos e Controles; Distribuição de Qui-Quadrado; República Tcheca/epidemiologia; Feminino; Frequência do Gene; Predisposição Genética para Doença; Heterozigoto; Homozigoto; Humanos; Modelos Logísticos; Masculino; Pessoa de Meia-Idade; Análise Multivariada; Razão de Chances; Fenótipo; Prevalência; Medição de Risco; Fatores de Risco; Fumar/epidemiologia; Acidente Vascular Cerebral/diagnóstico; Acidente Vascular Cerebral/epidemiologia; Trombofilia/sangue; Trombofilia/complicações; Trombofilia/diagnóstico; Trombofilia/epidemiologia; Adulto Jovem

Palavras-chave

Factor V Leiden (rs6025); Genetic epidemiology; Hypercoagulopathy; Ischemic stroke; Prothrombin G20210A (rs1799963); Smoking

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polimorfismo Genético / Protrombina / Fumar / Trombofilia / Acidente Vascular Cerebral Tipo de estudo: Diagnostic_studies / Etiology_studies / Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Limite: Aged80 País/Região como assunto: Europa Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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