Pro-Insulin-Like Growth Factor-II Ameliorates Age-Related Inefficient Regenerative Response by Orchestrating Self-Reinforcement Mechanism of Muscle Regeneration.

Ikemoto-Uezumi, Madoka; Uezumi, Akiyoshi; Tsuchida, Kunihiro; Fukada, So-ichiro; Yamamoto, Hiroshi; Yamamoto, Naoki; Shiomi, Kosuke; Hashimoto, Naohiro

Ikemoto-Uezumi, Madoka; Uezumi, Akiyoshi; Tsuchida, Kunihiro; Fukada, So-ichiro; Yamamoto, Hiroshi; Yamamoto, Naoki; Shiomi, Kosuke; Hashimoto, Naohiro.

Afiliação

Ikemoto-Uezumi M; Department of Regenerative Medicine, Research Institute, National Center for Geriatrics and Gerontology, Aichi, Japan.
Uezumi A; Division for Therapies against Intractable Diseases, Institute for Comprehensive Medical Science, Fujita Health University, Aichi, Japan.
Tsuchida K; Division for Therapies against Intractable Diseases, Institute for Comprehensive Medical Science, Fujita Health University, Aichi, Japan.
Fukada S; Laboratory of Molecular and Cellular Physiology, Graduate School of Pharmaceutical Sciences, Osaka University, Osaka, Japan.
Yamamoto H; Faculty of Pharmaceutical Sciences, Kobe Gakuin University, Kobe, Japan.
Yamamoto N; Laboratory of Molecular Biology and Histochemistry, Fujita Health University Joint Research Laboratory, Aichi, Japan.
Shiomi K; Department of Regenerative Medicine, Research Institute, National Center for Geriatrics and Gerontology, Aichi, Japan.
Hashimoto N; Department of Regenerative Medicine, Research Institute, National Center for Geriatrics and Gerontology, Aichi, Japan.

Stem Cells ; 33(8): 2456-68, 2015 Aug.

Article em En | MEDLINE | ID: mdl-25917344

Assuntos

Envelhecimento/metabolismo; Fator de Crescimento Insulin-Like II/metabolismo; Músculo Esquelético/fisiologia; Precursores de Proteínas/metabolismo; Regeneração/fisiologia; Células Satélites de Músculo Esquelético/metabolismo; Envelhecimento/genética; Animais; Fator de Crescimento Insulin-Like II/genética; Camundongos; Camundongos Knockout; Precursores de Proteínas/genética

Palavras-chave

Aging; Pro-insulin-like growth factor-II; Regeneration; Skeletal muscle

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Precursores de Proteínas / Regeneração / Envelhecimento / Fator de Crescimento Insulin-Like II / Músculo Esquelético / Células Satélites de Músculo Esquelético Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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