[Correlation of fractional exhaled nitric oxide with peripheral blood eosinophils and lung function in 1-3-year-old children with asthma].
Zhongguo Dang Dai Er Ke Za Zhi
; 17(4): 317-20, 2015 Apr.
Article
em Zh
| MEDLINE
| ID: mdl-25919547
ABSTRACT
OBJECTIVE:
To examine fractional exhaled nitric oxide (FeNO) values in 1-3-year-old children with asthma and analyze the correlation of FeNO with peripheral blood eosinophils (EOS) and lung function in these children.METHODS:
A total of 111 children aged 1-3 years with asthma were enrolled. The children were classified into acute exacerbation (n=62) and remission groups (n=49) according to their symptoms. FeNO values, lung function, and peripheral blood EOS count were measured in these children. Sixty age-matched healthy children were enrolled as the control group.RESULTS:
FeNO values were significantly higher in the acute exacerbation group (24.4 ppb) than in the remission group (18.0â ppb) and the control group (13.7â ppb) (P<0.05). The FeNO values in the remission group were significantly higher than in the control group (P<0.05). FeNO values were not significantly correlated with peripheral blood EOS count and lung function parameters (PEF, TEF25, TEF50, and TEF75).CONCLUSIONS:
Measurement of FeNO is useful to evaluate the disease activity in children with asthma aged 1 to 3 years, but the FeNO values are not correlated with peripheral blood EOS count and lung function.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Asma
/
Testes Respiratórios
/
Eosinófilos
/
Pulmão
/
Óxido Nítrico
Limite:
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
Idioma:
Zh
Ano de publicação:
2015
Tipo de documento:
Article