Genome-wide co-occupancy of AML1-ETO and N-CoR defines the t(8;21) AML signature in leukemic cells.

Trombly, Daniel J; Whitfield, Troy W; Padmanabhan, Srivatsan; Gordon, Jonathan A R; Lian, Jane B; van Wijnen, Andre J; Zaidi, Sayyed K; Stein, Janet L; Stein, Gary S

Trombly, Daniel J; Whitfield, Troy W; Padmanabhan, Srivatsan; Gordon, Jonathan A R; Lian, Jane B; van Wijnen, Andre J; Zaidi, Sayyed K; Stein, Janet L; Stein, Gary S.

Afiliação

Trombly DJ; Department of Cell and Developmental Biology, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA, 01655, USA. daniel.trombly@umassmed.edu.
Whitfield TW; Department of Cell and Developmental Biology, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA, 01655, USA. troy.whitfield@umassmed.edu.
Padmanabhan S; Program in Bioinformatics and Integrative Biology, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA, 01655, USA. troy.whitfield@umassmed.edu.
Gordon JA; Department of Cell and Developmental Biology, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA, 01655, USA. psrivats@yahoo.com.
Lian JB; Department of Biochemistry and Vermont Cancer Center, University of Vermont College of Medicine, 89 Beaumont Avenue, Burlington, VT, 05405, USA. jonathan.a.gordon@uvm.edu.
van Wijnen AJ; Department of Cell and Developmental Biology, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA, 01655, USA. jonathan.a.gordon@uvm.edu.
Zaidi SK; Department of Biochemistry and Vermont Cancer Center, University of Vermont College of Medicine, 89 Beaumont Avenue, Burlington, VT, 05405, USA. jane.lian@uvm.edu.
Stein JL; Department of Cell and Developmental Biology, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA, 01655, USA. jane.lian@uvm.edu.
Stein GS; Department of Cell and Developmental Biology, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA, 01655, USA. vanwijnen.andre@mayo.edu.

BMC Genomics ; 16: 309, 2015 Apr 17.

Article em En | MEDLINE | ID: mdl-25928846

Assuntos

Subunidade alfa 2 de Fator de Ligação ao Core/genética; Genoma Humano; Leucemia Mieloide Aguda/genética; Correpressor 1 de Receptor Nuclear/genética; Proteínas de Fusão Oncogênica/genética; Translocação Genética; Linhagem Celular Tumoral; Imunoprecipitação da Cromatina; Cromossomos Humanos Par 21; Cromossomos Humanos Par 8; Subunidade alfa 2 de Fator de Ligação ao Core/metabolismo; Humanos; Leucemia Mieloide Aguda/patologia; Correpressor 1 de Receptor Nuclear/metabolismo; Proteínas de Fusão Oncogênica/metabolismo; Regiões Promotoras Genéticas; Proteína 1 Parceira de Translocação de RUNX1; Análise de Sequência de DNA

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Translocação Genética / Leucemia Mieloide Aguda / Genoma Humano / Proteínas de Fusão Oncogênica / Subunidade alfa 2 de Fator de Ligação ao Core / Correpressor 1 de Receptor Nuclear Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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