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Topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study of dihydroxylated 2,6-diphenyl-4-aryl pyridines.
Karki, Radha; Song, Chanju; Kadayat, Tara Man; Magar, Til Bahadur Thapa; Bist, Ganesh; Shrestha, Aarajana; Na, Younghwa; Kwon, Youngjoo; Lee, Eung-Seok.
Afiliação
  • Karki R; College of Pharmacy, Yeungnam University, Gyeongsan 712-749, Republic of Korea.
  • Song C; College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Global Top 5 Program, Ewha Womans University, Seoul 120-750, Republic of Korea.
  • Kadayat TM; College of Pharmacy, Yeungnam University, Gyeongsan 712-749, Republic of Korea.
  • Magar TB; College of Pharmacy, Yeungnam University, Gyeongsan 712-749, Republic of Korea.
  • Bist G; College of Pharmacy, Yeungnam University, Gyeongsan 712-749, Republic of Korea.
  • Shrestha A; College of Pharmacy, Yeungnam University, Gyeongsan 712-749, Republic of Korea.
  • Na Y; College of Pharmacy, Cha University, Pochon 487-010, Republic of Korea.
  • Kwon Y; College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Global Top 5 Program, Ewha Womans University, Seoul 120-750, Republic of Korea. Electronic address: ykwon@ewha.ac.kr.
  • Lee ES; College of Pharmacy, Yeungnam University, Gyeongsan 712-749, Republic of Korea. Electronic address: eslee@yu.ac.kr.
Bioorg Med Chem ; 23(13): 3638-54, 2015 Jul 01.
Article em En | MEDLINE | ID: mdl-25936262
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piridinas / DNA Topoisomerases Tipo I / Proteínas de Ligação a DNA / Inibidores da Topoisomerase I / Inibidores da Topoisomerase II / Antineoplásicos Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piridinas / DNA Topoisomerases Tipo I / Proteínas de Ligação a DNA / Inibidores da Topoisomerase I / Inibidores da Topoisomerase II / Antineoplásicos Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article