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ROR1-targeted delivery of OSU-2S, a nonimmunosuppressive FTY720 derivative, exerts potent cytotoxicity in mantle-cell lymphoma in vitro and in vivo.
Mani, Rajeswaran; Chiang, Chi-Ling; Frissora, Frank W; Yan, Ribai; Mo, Xiaokui; Baskar, Sivasubramanian; Rader, Christoph; Klisovic, Rebecca; Phelps, Mitch A; Chen, Ching-Shih; Lee, Robert J; Byrd, John C; Baiocchi, Robert; Lee, L James; Muthusamy, Natarajan.
Afiliação
  • Mani R; Division of Hematology, Department of Internal Medicine, College of Medicine, The Ohio State University, Columbus, OH, USA; Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA; Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, Colu
  • Chiang CL; Division of Hematology, Department of Internal Medicine, College of Medicine, The Ohio State University, Columbus, OH, USA; Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA; Center for Affordable Nanoengineering of Polymeric Biomedical Devices, The Ohio State University, Col
  • Frissora FW; Division of Hematology, Department of Internal Medicine, College of Medicine, The Ohio State University, Columbus, OH, USA; Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA.
  • Yan R; Division of Medicinal Chemistry, College of Pharmacy, The Ohio State University, Columbus, OH, USA.
  • Mo X; Center for Biostatistics, The Ohio State University, Columbus, OH, USA.
  • Baskar S; Genetics Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.
  • Rader C; Department of Cancer Biology and Department of Molecular Therapeutics, The Scripps Research Institute, Scripps Florida, Jupiter, FL, USA.
  • Klisovic R; Division of Hematology, Department of Internal Medicine, College of Medicine, The Ohio State University, Columbus, OH, USA.
  • Phelps MA; Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA; Division of Pharmaceutics, College of Pharmacy, The Ohio State University, Columbus, OH, USA.
  • Chen CS; Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA; Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, Columbus, OH, USA; Division of Medicinal Chemistry, College of Pharmacy, The Ohio State University, Columbus, OH, USA.
  • Lee RJ; Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA; Center for Affordable Nanoengineering of Polymeric Biomedical Devices, The Ohio State University, Columbus, OH, USA; Division of Pharmaceutics, College of Pharmacy, The Ohio State University, Columbus, OH, USA.
  • Byrd JC; Division of Hematology, Department of Internal Medicine, College of Medicine, The Ohio State University, Columbus, OH, USA; Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA; Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, Colu
  • Baiocchi R; Division of Hematology, Department of Internal Medicine, College of Medicine, The Ohio State University, Columbus, OH, USA; Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA; Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, Colu
  • Lee LJ; Center for Affordable Nanoengineering of Polymeric Biomedical Devices, The Ohio State University, Columbus, OH, USA; Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, OH, USA.
  • Muthusamy N; Division of Hematology, Department of Internal Medicine, College of Medicine, The Ohio State University, Columbus, OH, USA; Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA; Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, Colu
Exp Hematol ; 43(9): 770-4.e2, 2015 Sep.
Article em En | MEDLINE | ID: mdl-25937048
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Propilenoglicóis / Esfingosina / Sistemas de Liberação de Medicamentos / Linfoma de Célula do Manto / Citotoxinas / Receptores Órfãos Semelhantes a Receptor Tirosina Quinase Limite: Animals / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Propilenoglicóis / Esfingosina / Sistemas de Liberação de Medicamentos / Linfoma de Célula do Manto / Citotoxinas / Receptores Órfãos Semelhantes a Receptor Tirosina Quinase Limite: Animals / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article