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A Monoclonal Antibody to ADAM17 Inhibits Tumor Growth by Inhibiting EGFR and Non-EGFR-Mediated Pathways.
Rios-Doria, Jonathan; Sabol, Darrin; Chesebrough, Jon; Stewart, Dave; Xu, Linda; Tammali, Ravinder; Cheng, Li; Du, Qun; Schifferli, Kevin; Rothstein, Ray; Leow, Ching Ching; Heidbrink-Thompson, Jenny; Jin, Xiaofang; Gao, Changshou; Friedman, Jay; Wilkinson, Brandy; Damschroder, Melissa; Pierce, Andrew J; Hollingsworth, Robert E; Tice, David A; Michelotti, Emil F.
Afiliação
  • Rios-Doria J; Oncology Research, MedImmune, LLC, Gaithersburg, Maryland.
  • Sabol D; Oncology Research, MedImmune, LLC, Gaithersburg, Maryland.
  • Chesebrough J; Oncology Research, MedImmune, LLC, Gaithersburg, Maryland.
  • Stewart D; Oncology Research, MedImmune, LLC, Gaithersburg, Maryland.
  • Xu L; Oncology Research, MedImmune, LLC, Gaithersburg, Maryland.
  • Tammali R; Oncology Research, MedImmune, LLC, Gaithersburg, Maryland.
  • Cheng L; Oncology Research, MedImmune, LLC, Gaithersburg, Maryland.
  • Du Q; Oncology Research, MedImmune, LLC, Gaithersburg, Maryland.
  • Schifferli K; Oncology Research, MedImmune, LLC, Gaithersburg, Maryland.
  • Rothstein R; Oncology Research, MedImmune, LLC, Gaithersburg, Maryland.
  • Leow CC; Oncology Research, MedImmune, LLC, Gaithersburg, Maryland.
  • Heidbrink-Thompson J; Oncology Research, MedImmune, LLC, Gaithersburg, Maryland.
  • Jin X; Oncology Research, MedImmune, LLC, Gaithersburg, Maryland.
  • Gao C; Oncology Research, MedImmune, LLC, Gaithersburg, Maryland.
  • Friedman J; Champions Oncology Inc., Baltimore, Maryland.
  • Wilkinson B; Champions Oncology Inc., Baltimore, Maryland.
  • Damschroder M; Oncology Research, MedImmune, LLC, Gaithersburg, Maryland.
  • Pierce AJ; Oncology Research, MedImmune, LLC, Gaithersburg, Maryland.
  • Hollingsworth RE; Oncology Research, MedImmune, LLC, Gaithersburg, Maryland.
  • Tice DA; Oncology Research, MedImmune, LLC, Gaithersburg, Maryland.
  • Michelotti EF; Oncology Research, MedImmune, LLC, Gaithersburg, Maryland. michelottie@medimmune.com.
Mol Cancer Ther ; 14(7): 1637-49, 2015 Jul.
Article em En | MEDLINE | ID: mdl-25948294
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Ensaios Antitumorais Modelo de Xenoenxerto / Proteínas ADAM / Receptores ErbB / Anticorpos Monoclonais / Neoplasias Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Ensaios Antitumorais Modelo de Xenoenxerto / Proteínas ADAM / Receptores ErbB / Anticorpos Monoclonais / Neoplasias Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article