Amniotic fluid LPCAT1 mRNA correlates with the lamellar body count.
J Perinat Med
; 44(5): 531-2, 2016 Jul 01.
Article
em En
| MEDLINE
| ID: mdl-25968427
ABSTRACT
Lysophosphatidylcholine acyltransferase 1 (LPCAT1) is required in the biosynthesis of pulmonary surfactant. This short communication describes our assessment of LPCAT1 mRNA levels in human amniotic fluid. We found a direct correlation between LPCAT1 mRNA copies and the amniotic fluid lamellar body count (LBC). This finding corroborates an association between LPCAT1 and surfactant phospholipid biosynthesis in humans. It may provide a model for future research in perinatal medicine.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
RNA Mensageiro
/
Líquido Amniótico
/
1-Acilglicerofosfocolina O-Aciltransferase
Tipo de estudo:
Prognostic_studies
Limite:
Female
/
Humans
/
Newborn
/
Pregnancy
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article