Hospital Authority audit of the outcome of endoscopic resection of superficial upper gastro-intestinal lesions in Hong Kong.
Hong Kong Med J
; 21(3): 224-31, 2015 Jun.
Article
em En
| MEDLINE
| ID: mdl-25999031
ABSTRACT
OBJECTIVES:
To review the short-term outcome of endoscopic resection of superficial upper gastro-intestinal lesions in Hong Kong.DESIGN:
Historical cohort study.SETTING:
All Hospital Authority hospitals in Hong Kong. PATIENTS This was a multicentre retrospective study of all patients who underwent endoscopic resection of superficial upper gastro-intestinal lesions between January 2010 and June 2013 in all government-funded hospitals in Hong Kong. MAIN OUTCOMEMEASURES:
Indication of the procedures, peri-procedural and procedural parameters, oncological outcomes, morbidity, and mortality.RESULTS:
During the study period, 187 lesions in 168 patients were resected. Endoscopic mucosal resection was performed in 34 (18.2%) lesions and endoscopic submucosal dissection in 153 (81.8%) lesions. The mean size of the lesions was 2.6 (standard deviation, 1.8) cm. The 30-day morbidity rate was 14.4%, and perforations and severe bleeding occurred in 4.3% and 3.2% of the patients, respectively. Among patients who had dysplasia or carcinoma, R0 resection was achieved in 78% and the piecemeal resection rate was 11.8%. Lateral margin involvement was 14% and vertical margin involvement was 8%. Local recurrence occurred in 9% of patients and 15% had residual disease. The 2-year overall survival rate and disease-specific survival rate was 90.6% and 100%, respectively.CONCLUSION:
Endoscopic mucosal resection and endoscopic submucosal dissection were introduced in low-to-moderate-volume hospitals with acceptable morbidity rates. The short-term survival was excellent. However, other oncological outcomes were higher than those observed in high-volume centres and more secondary procedures were required.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Gástricas
/
Neoplasias Esofágicas
/
Carcinoma
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Adenoma
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Hemorragia Pós-Operatória
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Neoplasias Duodenais
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Perfuração Intestinal
Tipo de estudo:
Observational_studies
Limite:
Aged
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Female
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Humans
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Male
/
Middle aged
País/Região como assunto:
Asia
Idioma:
En
Ano de publicação:
2015
Tipo de documento:
Article