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Exposure to the androgenic brominated flame retardant 1,2-dibromo-4-(1,2-dibromoethyl)-cyclohexane alters reproductive and aggressive behaviors in birds.
Marteinson, Sarah C; Letcher, Robert J; Fernie, Kimberly J.
Afiliação
  • Marteinson SC; Ecotoxicology and Wildlife Health Division, Science and Technology Branch, Environment Canada, Burlington, Ontario, Canada.
  • Letcher RJ; Ecotoxicology and Wildlife Health Division, Science and Technology Branch, Environment Canada, National Wildlife Research Centre, Ottawa, Ontario, Canada.
  • Fernie KJ; Ecotoxicology and Wildlife Health Division, Science and Technology Branch, Environment Canada, Burlington, Ontario, Canada.
Environ Toxicol Chem ; 34(10): 2395-402, 2015 Oct.
Article em En | MEDLINE | ID: mdl-26013366
Detected in environmental samples, 1,2-dibromo-4-(1,2-dibromoethyl) cyclohexane (DBE-DBCH) is a bioaccumulative isomer of a current-use brominated flame retardant. All 4 structural isomers are androgen agonists; however, little toxicological information exists for this compound. The objective of the present study was to determine if ß-DBE-DBCH, the isomer found most prominently in animal tissue, affects androgen-dependent behavior of breeding American kestrels (Falco sparverius). The authors hypothesized that if ß-DBE-DBCH acts as an androgen agonist in kestrels, androgen-dependent behaviors (i.e., copulation, courtship, aggression) would increase and behaviors inhibited by androgens (i.e., parental care behaviors) would decrease. Sixteen captive experimental kestrel pairs were exposed to 0.239 ng ß-DBE-DBCH/g kestrel/d by diet from 4 wk prior to pairing until their nestlings hatched (mean 82 d) and compared with vehicle only-exposed control pairs (n = 15). Androgen-dependent behaviors were significantly increased in ß-DBE-DBCH-exposed birds, consistent with the authors' hypothesis. These behavioral changes included copulation and other sexual behaviors in males and females and aggression in males, suggesting that ß-DBE-DBCH may have acted like an androgen agonist in these birds. Parental behaviors were not reduced in exposed birds as predicted, although dietary exposure had ceased before chicks hatched. Further assessment of ß-DBE-DBCH is recommended given these behavioral changes and the previously reported reproductive changes in the same birds.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Reprodução / Cicloexanos / Agressão / Falconiformes / Exposição Ambiental / Poluentes Ambientais / Retardadores de Chama / Androgênios Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2015 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Reprodução / Cicloexanos / Agressão / Falconiformes / Exposição Ambiental / Poluentes Ambientais / Retardadores de Chama / Androgênios Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2015 Tipo de documento: Article