Generation and characterization of a trackable plant-made influenza H5 virus-like particle (VLP) containing enhanced green fluorescent protein (eGFP).

Young, Katie R; Arthus-Cartier, Guillaume; Yam, Karen K; Lavoie, Pierre-Olivier; Landry, Nathalie; D'Aoust, Marc-André; Vézina, Louis-Philippe; Couture, Manon M-J; Ward, Brian J

Young, Katie R; Arthus-Cartier, Guillaume; Yam, Karen K; Lavoie, Pierre-Olivier; Landry, Nathalie; D'Aoust, Marc-André; Vézina, Louis-Philippe; Couture, Manon M-J; Ward, Brian J.

Afiliação

Young KR; *Research Institute of McGill University Health Centre and Department of Experimental Medicine, McGill University, Montréal, Québec, Canada; and Medicago, Incorporated, Québec, Québec, Canada.
Arthus-Cartier G; *Research Institute of McGill University Health Centre and Department of Experimental Medicine, McGill University, Montréal, Québec, Canada; and Medicago, Incorporated, Québec, Québec, Canada.
Yam KK; *Research Institute of McGill University Health Centre and Department of Experimental Medicine, McGill University, Montréal, Québec, Canada; and Medicago, Incorporated, Québec, Québec, Canada.
Lavoie PO; *Research Institute of McGill University Health Centre and Department of Experimental Medicine, McGill University, Montréal, Québec, Canada; and Medicago, Incorporated, Québec, Québec, Canada.
Landry N; *Research Institute of McGill University Health Centre and Department of Experimental Medicine, McGill University, Montréal, Québec, Canada; and Medicago, Incorporated, Québec, Québec, Canada.
D'Aoust MA; *Research Institute of McGill University Health Centre and Department of Experimental Medicine, McGill University, Montréal, Québec, Canada; and Medicago, Incorporated, Québec, Québec, Canada.
Vézina LP; *Research Institute of McGill University Health Centre and Department of Experimental Medicine, McGill University, Montréal, Québec, Canada; and Medicago, Incorporated, Québec, Québec, Canada.
Couture MM; *Research Institute of McGill University Health Centre and Department of Experimental Medicine, McGill University, Montréal, Québec, Canada; and Medicago, Incorporated, Québec, Québec, Canada.
Ward BJ; *Research Institute of McGill University Health Centre and Department of Experimental Medicine, McGill University, Montréal, Québec, Canada; and Medicago, Incorporated, Québec, Québec, Canada brian.ward@mcgill.ca.

FASEB J ; 29(9): 3817-27, 2015 Sep.

Article em En | MEDLINE | ID: mdl-26038124

Assuntos

Anticorpos Antivirais/imunologia; Proteínas de Fluorescência Verde; Virus da Influenza A Subtipo H5N1; Vacinas contra Influenza; Nicotiana; Plantas Geneticamente Modificadas; Animais; Feminino; Proteínas de Fluorescência Verde/biossíntese; Proteínas de Fluorescência Verde/genética; Proteínas de Fluorescência Verde/imunologia; Proteínas de Fluorescência Verde/farmacologia; Virus da Influenza A Subtipo H5N1/genética; Virus da Influenza A Subtipo H5N1/imunologia; Vacinas contra Influenza/biossíntese; Vacinas contra Influenza/genética; Vacinas contra Influenza/imunologia; Vacinas contra Influenza/farmacologia; Camundongos; Camundongos Endogâmicos BALB C; Plantas Geneticamente Modificadas/genética; Plantas Geneticamente Modificadas/metabolismo; Nicotiana/genética; Nicotiana/metabolismo

Palavras-chave

H5 hemagglutinin; fluorescent particle; immune response; particle assembly

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Nicotiana / Vacinas contra Influenza / Plantas Geneticamente Modificadas / Proteínas de Fluorescência Verde / Virus da Influenza A Subtipo H5N1 / Anticorpos Antivirais Limite: Animals Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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