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Modular synthesis and biological activity of pyridyl-based analogs of the potent Class I Histone Deacetylase Inhibitor Largazole.
Clausen, Dane J; Smith, William B; Haines, Brandon E; Wiest, Olaf; Bradner, James E; Williams, Robert M.
Afiliação
  • Clausen DJ; Department of Chemistry, Colorado State University, Fort Collins, CO 80523, USA.
  • Smith WB; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA.
  • Haines BE; Department of Chemistry & Biochemistry, University of Notre Dame, Notre Dame, IN 46556, USA.
  • Wiest O; Department of Chemistry & Biochemistry, University of Notre Dame, Notre Dame, IN 46556, USA.
  • Bradner JE; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA.
  • Williams RM; Department of Chemistry, Colorado State University, Fort Collins, CO 80523, USA; University of Colorado Cancer Center, Aurora, CO 80045, USA. Electronic address: robert.williams@colostate.edu.
Bioorg Med Chem ; 23(15): 5061-5074, 2015 Aug 01.
Article em En | MEDLINE | ID: mdl-26054247
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tiazóis / Depsipeptídeos / Inibidores de Histona Desacetilases / Histona Desacetilases Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tiazóis / Depsipeptídeos / Inibidores de Histona Desacetilases / Histona Desacetilases Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article